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The pressure of R-410A is significantly higher than other refrigerants R-22 and R-404A. This does not mean that R-410A, or equipment containing R-410A is unsafe. It does mean that technicians must use AC equipment; cylinders and service tools have been re-engineered to handle these higher pressures.

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Q: Why are there more safety precautions with r410a than with other popular refrigerants like r22 and r404a?
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