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Cancer of the large intestine and rectum?

Updated: 12/13/2023
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13y ago

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Cancer of the large intestine and rectum is collectively known as colorectal cancer. Colorectal cancer typically develops from precancerous polyps, which are abnormal growths in the lining of the colon or rectum. Over time, these polyps may become cancerous, leading to the formation of tumors.

Here are key points about colorectal cancer:

Risk Factors:

Age: The risk of colorectal cancer increases with age, with the majority of cases diagnosed in individuals over 50.

Family History and Genetics: Individuals with a family history of colorectal cancer or certain genetic conditions, such as Lynch syndrome or familial adenomatous polyposis (FAP), may have an increased risk.

Personal History of Polyps or Inflammatory Bowel Disease: Individuals with a history of colorectal polyps or inflammatory bowel diseases, such as ulcerative colitis or Crohn's disease, are at a higher risk.

Lifestyle Factors: Unhealthy lifestyle choices, such as a diet high in red and processed meats, low physical activity, smoking, and heavy alcohol consumption, may contribute to an increased risk.

Race and Ethnicity: African Americans have a higher incidence of colorectal cancer compared to some other racial and ethnic groups.

Symptoms:

Change in Bowel Habits: Persistent diarrhea, constipation, or a change in stool consistency.

Blood in the Stool: Rectal bleeding or the presence of dark, tarry stools.

Abdominal Discomfort: Cramps, pain, or discomfort in the abdominal area.

Unexplained Weight Loss: Significant and unexplained weight loss without changes in diet or physical activity.

Fatigue: Persistent fatigue or weakness.

Diagnosis and Staging:

Colonoscopy: A key diagnostic tool that allows a doctor to examine the entire colon and rectum and detect and remove polyps.

Biopsy: If suspicious areas are found during a colonoscopy, a biopsy may be performed to determine if the tissue is cancerous.

Imaging: CT scans, MRIs, and other imaging tests may be used to determine the extent of the cancer (staging) and whether it has spread to other organs.

Treatment:

Surgery: The primary treatment involves surgical removal of the tumor and, in some cases, nearby lymph nodes.

Chemotherapy: Medications may be used to kill cancer cells or stop their growth.

Radiation Therapy: High-energy rays are used to target and destroy cancer cells.

Targeted Therapy and Immunotherapy: These newer treatment approaches target specific molecules involved in cancer growth or stimulate the immune system to fight cancer.

Prevention and Early Detection:

Screening: Regular screening, such as colonoscopies, can detect and remove precancerous polyps before they become cancerous.

Healthy Lifestyle: Adopting a healthy lifestyle, including a balanced diet rich in fruits and vegetables, regular physical activity, limited alcohol consumption, and avoiding tobacco, may help reduce the risk.

Colorectal cancer is often treatable and, in many cases, preventable with early detection and appropriate interventions. Regular screenings are crucial, especially for individuals with risk factors or those aged 50 and older. If you have concerns about colorectal cancer or notice any symptoms, it's essential to consult with a healthcare professional for evaluation and appropriate screening recommendations.

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raghu.punarjan

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Colon Cancer

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Q: Cancer of the large intestine and rectum?
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