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Churg Strauss Syndrome is a rare systemic autoimmune disease characterized by inflammation of small to medium sized arteries, arterioles and venules. This inflammatory process of blood vessels is more commonly known as vasculitis. Churg Strauss vasculitis is characterized by the invasion and abnormal increase of a white blood cell known as an eosinophil. The eosinophils cluster together and release harmful granules that collect in different parts of the body as inflammatory nodule lesions. This is called granulomatosis. This eosinophilic inflammation, along with Asthma, are the hallmarks of Churg Strauss Syndrome. The inflammatory process can cause impaired blood flow to various organ systems. The resultant damage to different organs may be temporary or permanent.
Churg Strauss Syndrome should be considered when there is late onset asthma, or worsening asthma, along with either numbness or pain in the extremities, sinus problems, a lingering cough, a rash, stomach problems, or symptoms of cardiac involvement.
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Can Polyarteritis nodosa cause Churg-Strauss syndrome?
Churg-Strauss syndrome can cause Vasculitic neuropathy
What does it mean when you eosionphils are too high?
Churg-Strauss Syndrome if you also have eosionphillic esophagitis
What are the symptoms of Churg Strauss syndrome?
Asthma, hay fever, sinus pain and inflammation, weight loss, loss of appetite, fatigue, cough abdominal pain, gastrointestinal bleeding, rash or skin sores
Does Mepolizumab cause hair loss?
Mepolizumab (a monoclonal antibody against interleukin-5) is a safe and well-tolerated therapy that will allow for steroid tapering in patients with steroid-dependent Churg-Strauss Syndrome (CSS). There is nothing which says it causes hair loss, but can be that in some cases you experience it.
What causes vasculitis?
The cause of vasculitis diseases is usually not known. is understood that immune system abnormality leading to inflammation is the most common feature. The characteristics and symptoms of the disease depend on what particular organs are affected. Vasculitis include diseases succh as Kawasaki disease, Behcet's disease, polyarteritis nodosa, Wegener's granulomatosis, cryoglobulinemia, Takayasu's arteritis, Churg-Strauss syndrome, giant cell arteritis (temporal arteritis), and Henoch-Schönlein purpura.
What does a high level of esinophils 576 in the blood mean?
This from: Center for Eosinophilic Disorder at Cincinnati's Children's Hospital @ http://www.cincinnatichildrens.org/svc/alpha/e/eosinophilic/about/conditions.htm There are many disorders where the eosinophils have been found elevated either in the blood or in different tissues. The experts in the Cincinnati Center for Eosinophilic Disorder at Cincinnati Children's Hospital Medical Center provide a list of general categories of diseases with some examples included. Allergic Disorders: Allergic disorders are classically characterized by presence of eosinophils. Allergic rhinoconjunctivitis (hay fever) has increased levels of eosinophils in the nasal mucosa. Asthma, after an exacerbation, shows increased eosinophils in the lung. Drug Reactions: Any drug/medicine can precipitate a reaction. Some of these reactions are allergic in nature and eosinophils might be elevated in blood or in tissues where the drug is concentrated. Infectious Diseases: Parasitic infections (Helminthiasis-worms), fungal infections and some other types of infections are associated with increased eosinophils. Blood Disorders: A few examples of hematologic disorders with increased esoinophils include the hypereosinophilic syndrome, leukemias, lymphomas, tumors, mastocytosis and atheroembolic disease. Immunologic Disorders and Reactions: Hyper-IgE syndrome, Ommen's syndrome, thymomas, transplant rejections are only a few types of conditions with increased eosinophils. Endocrine Disorders: Hypoadrenalism has been associated with blood eosinophilia. • • • • • • • • • Specific Organ Involvement: Below are certain conditions organized by the organs/tissues that are affected where eosinophils have been found to be increased or pathologically present. Skin and subcutaneous disorders Atopic dermatitis (eczema), bullous pemphigoid, pemphigus vulgaris, dermatitis herpetiformis, drug-induced lesions, urticaria, eosinophilic panniculitis, angioedema with eosinophilia, Kimura's disease, Shulman's syndrome, Well's syndrome, eosinophilic ulcer of the oral mucosa, eosinophilic pustular folliculitis and recurrent cutaneous necrotizing eosinophilic vaculitis. Pulmonary conditions Drug/Toxin-induced eosinophilic lung disease, Loeffler's syndrome, allergic bronchopulmonary aspergillosis, eosinophilic pneumonia, Churg-Strauss syndrome, eosinophilic granuloma, pleural eosinophilia. Gastrointestinal diseases Gastroesophageal reflux, parasitic infections, fungal infections, Helicobacter pylori infections, inflammatory bowel disease (ulcerative colitis and Crohn's disease), food allergic disorders, protein-induced enteropathy and protein-induced enterocolitis, allergic colitis, celiac disease, primary eosinophilic esophagitis, gastroenteritis and colitis. Rare tumors (leiomyomatosis), connective tissue disorders and vasculitic disorders. Neurologic disorders Organizing chronic subdural hematoma membranes, central nervous system infections, ventriculoperitoneal shunts, drug-induced adverse reactions. Rheumatologic illnesses Eosinophilic synovitis, eosinophilia-myalgia syndrome, vaculitic disorders such as the Churg-Strauss Syndrome. Cardiac conditions Heart damage has been reported secondary to systemic disorders such as the hypereosinophilic syndrome or the Churg-Strauss syndrome. Certain congenital heart conditions (septal defects, aortic stenosis) are associated with blood esoinophilia. Renal diseases Eosinophiluria (eosinophils in the urine) associated with infections or interstitial nephritis and eosinophilic cystitis.
What are two types of arthritis?
There are many types of arthritis: Achilles tendinitis, Achondroplasia, Acromegalic arthropathy, Adhesive capsulitis, Adult onset Still's disease, Amyloidosis, Ankylosing spondylitis, Anserine bursitis, Avascular necrosis, Behcet's syndrome, Bicipital tendinitis, Blount's disease, Brucellar spondylitis, Bursitis, Calcaneal bursitis, Calcium pyrophosphate dihydrate (CPPD), crystal deposition disease, Caplan's syndrome, Carpal tunnel syndrome, Chondrocalcinosis, Chondromalacia patellae, Chronic synovitis, Chronic recurrent multifocal osteomyelitis, Churg-Strauss syndrome, Cogan's syndrome, Corticosteroid-induced osteoporosis, Costosternal syndrome, CREST syndrome, Cryoglobulinemia, Degenerative joint disease, Dermatomyositis, Diabetic finger sclerosis, Diffuse idiopathic skeletal hyperostosis (DISH), Discitis, Discoid lupus erythematosus, Drug-induced lupus, Duchenne's muscular dystrophy, Dupuytren's contracture, Ehlers-Danlos syndrome, Enteropathic arthritis, Epicondylitis, Erosive inflammatory osteoarthritis, Exercise-induced compartment syndrome, Fabry's disease, Familial Mediterranean fever, Farber's lipogranulomatosis, Felty's syndrome, Fibromyalgia, Fifth's disease, Flat feet, Foreign body synovitis, Freiberg's disease, Fungal arthritis, Gaucher's disease, Giant cell arteritis, Gonococcal arthritis, Goodpasture's syndrome, Gout, Granulomatous arteritis, Hemarthrosis, Hemochromatosis, Henoch-Schonlein purpura, Hepatitis B surface antigen disease, Hip dysplasia, HIV induced inflammatory arthritis, Hurler syndrome, Hypermobility syndrome, Hypersensitvity vasculitis, Hypertrophic osteoarthropathy, Immune complex disease, Impingement syndrome, Jaccoud's arthropathy, Juvenile ankylosing spondylitis, Juvenile dermatomyositis, Juvenile rheumatoid arthritis, Kawasaki disease, Kienbock's disease, Legg-Calve-Perthes disease, Lesch-Nyhan syndrome, Linear scleroderma, Lipoid dermatoarthritis, Lofgren's syndrome, Lyme disease, Malignant synovioma, Marfan's syndrome, Medial plica syndrome, Metastatic carcinomatous arthritis, Mixed connective tissue disease (MCTD), Mixed cryoglobulinemia, Mucopolysaccharidosis, Multicentric reticulohistiocytosis, Multiple epiphyseal dysplasia, Mycoplasmal arthritis, Myofascial pain syndrome, Neonatal lupus, Neuropathic arthropathy, Nodular panniculitis, Ochronosis, Olecranon bursitis, Osgood-Schlatter?s disease, Osteoarthritis, Osteochondromatosis, Osteogenesis imperfecta, Osteomalacia, Osteomyelitis, Osteonecrosis, Osteoporosis, Overlap syndrome, Pachydermoperiostosis, Paget's disease of bone, Palindromic rheumatism, Patellofemoral pain syndrome, Pellegrini-Stieda syndrome, Pigmented villonodular synovitis, Piriformis syndrome, Plantar fasciitis, Polyarteritis nodosa, Polymyalgia rheumatica, Polymyositis, Popliteal cysts, Posterior tibial tendinitis, Pott's disease, Prepatellar bursitis, Prosthetic joint infection, Pseudoxanthoma elasticum, Psoriatic arthritis, Raynaud's phenomenon, Reactive arthritis/Reiter's syndrome, Reflex sympathetic dystrophy syndrome, Relapsing polychondritis, Retrocalcaneal bursitis, Rheumatic fever, Rheumatoid arthritis, Rheumatoid vasculitis, Rotator cuff tendinitis, Sacroiliitis, Salmonella osteomyelitis, Sarcoidosis, Saturnine gout, Scheuermann's osteochondritis, Scleroderma, Septic arthritis, Seronegative arthritis, Shigella arthritis, Shoulder-hand syndrome, Sickle cell arthropathy, Sjogren's syndrome, Slipped capital femoral epiphysis, Spinal stenosis, Spondylolysis, Staphylococcus arthritis, Stickler syndrome, Subacute cutaneous lupus, Sweet's syndrome, Sydenham's chorea, Syphilitic arthritis, Systemic lupus erythematosus (SLE), Takayasu's arteritis, Tarsal tunnel syndrome Tennis elbow, Tietse's syndrome, Transient osteoporosis, Traumatic arthritis, Trochanteric bursitis, Tuberculosis arthritis, Arthritis of Ulcerative colitis, Undifferentiated connective tissue syndrome (UCTS), Urticarial vasculitis, Viral arthritis, Wegener's granulomatosis, Whipple's disease, Wilson's disease and Yersinial arthritis. That's 171 types!
What are the 100 forms of arthritis?
Forms of arthritis and associated diseasesLupus, Lyme Disease, Adult Onset Still's Disease, Marfan Syndrome, Ankylosing Spondylitis, Mycotic Arthritis, Osgood-Schlatter Disease, Osteitis Deformans, Aseptic Necrosis, Osteoarthritis, Avascular Necrosis, Osteonecrosis, Basal Joint Arthritis, Osteoporosis, Behcet's Disease, Bursitis, Paget's Disease of Bone, Carpal Tunnel Syndrome, Palindromic Rheumatism, Celiac Disease, Polyarteritis Nodosa, CMC Arthritis, Polymyalgia Rheumatica, Complex Regional Pain, Polymyositis, Costochondritis, Pseudogout, Psoriatic Arthritis, Crohn's Disease, Raynaud's phenomenon, Degenerative Joint Disease, Dermatomyositis, Reiter's Syndrome, Discoid Lupus, Erythematosus, Ehlers-Danlos Syndrome, Rheumatic Fever, Eosinophilic Fasciitis, Rheumatoid Arthritis, Felty Syndrome, Scleroderma, Fibro myalgia, Septic Arthritis, Fifth Disease, Sjogren's Syndrome, Forestier Disease, Somatotroph Adenoma, Fungal Arthritis, Spinal Stenosis, Gaucher Disease, Takayasu Arteritis, Giant Cell Arteritis, Temporal Arteritis Gonococcal Arthritis, Tendonitis, Gout, Tietze's Syndrome, Henoch-Schonlein Purpura, TMJ / TMD, Infectious Arthritis, Tuberculous Arthritis. Inflammatory Bowel Disease, Ulcerative Colitis, Joint Hyper mobility, Vasculitis, Juvenile Arthritis, Viral Arthritis, Kawasaki Disease, Wegener's Granulomatosis, Legg-Calve-Perthes Disease,
My lung biopsy says I have large and medium vessel Vasculitis my blood work says I don't. The biopsy was done before the bloodwork. Which do you believe?
I was diagnoised with churg Strauss syndrome April 2008 this is a form of vasculitis which effects my medium sized blood vessels. I am taking steriods for it. When my consultant took me off my steriods in August 2008 thinking my condition was mild and would not flare up within 4 weeks my white ens. cell count did not show raised inflamation levels to cause him concern but after I complained that I felt my vasculitis was back and was worse than ever he only believed me when I had an xray and he could see from the xray that my white ens. cells were present again only then did he believe me when I said I could feel the white cells crawling in my lungs again from this I personally have concluded that a blood test with a low level of inflamation indicators does not mean that my vasculitis is been controlled and kept at bay to prevent tissue and organ damage because of this I have lost complete and utter faith in my consultant and I only go on how I am feeling in myself. When I was admitted to hospital April 2008 my white ens. cell count was in the billions instead of the normal millions. In answer to your question going on my own experience I would believe your biopsy especially if you are taking steriods for your condition like I am. I personally do not think that the doctors know 100 per cent what they are talking about only you can decide whether you are ill or not not a blood test. I hope this reply helps you.
