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First signs of toxicity are-anorexia,nausea and vomiting

CNS-headache,drowsiness,facial pain and depression

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Q: Common adverse effects of digoxin
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When would you withhold digoxin or linoxon?

The rule of thumb is 'Nausea'. When the patient feels like vomiting, he may be getting overdose of digoxin. Otherwise, there may be hypokalemia or low level of potassium. Most common cause for the same is no food intake or loose motion. If you continue to give digoxin, patient will go for vomiting. Natures way to get rid of digoxin. if you continue to give digoxin, you have serious side effects, like digoxin induced cardiac arrhythmias.


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How does the hypokalemia affect the effects of Digitalis?

Hypokalemia potentiates the effects of digoxin. Hypokalemia reduces the drive of the Na-K-ATPase, resulting in increased cellular Na in cardiac muscles. Digoxin does the same thing by blocking the Na-K-ATPase.


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Digoxin belongs to a class of cardiovascular drugs known as cardiac glycosides. According to Drugs.com, a drug information website that provides peer-reviewed information to consumers, digoxin is used to treat heart failure and abnormal heart rhythms known as arrhythmias. Digoxin is also used to treat angina and can be used after a heart attack. Digoxin has several potential side effects.Read more: http://www.livestrong.com/article/180080-the-effects-of-digoxin/#ixzz2QQ0kne9W


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What is digitalis or a drug called digoxin?

Digitalis has got digoxin and digitoxin in the extract of the plant Digitalis lanata. Digitoxin has got very long half life and should not be used in therapeutics. Digoxin is drug of therapeutic value. It is very good drug for congestive heart failure. Digoxin has very unique mode of action. It takes less oxygen for heart to do the same amount of work. Alternately, your heart work more with the same amount of oxygen, when on digoxin. You may give the loading dose of two tablets of 0.25 mg. Fallowed by one after say twelve hours. Then 3/4 tablet daily after 24 hours. When there is no urgency, you should give 3/4 tablet daily, from the begining. You may need to give potassium supplement in some, specially when the patient is taking no food for a day or two. With signs of toxic effects, you should stop the drug. The rule of thumb is 'Nausea'. When the patient feels like vomiting, he may be getting overdose of digoxin. Otherwise, there may be hypokalemia or low level of potassium. Most common cause for the same is no food intake or loose motion. If you continue to give digoxin, patient will go for vomiting. Natures way to get rid of digoxin. if you continue to give digoxin, you have serious side effects, like digoxin induced cardiac arrhythmias.