If you're using MasteringBiology on this then look at the third hint and you'll be able to figure it out.
Seriously, look at the third hint if you can to better understand it. It includes pictures.
If you can't or are just too lazy to, here's what I got:
1) Cortisol passes through the plasma membrane into the cytoplasm.
2) Cortisol-receptor complex forms in the cytoplasm.
3) Cortisol-receptor complex enters the nucleus where it binds to genes.
4) Cortisol-receptor complex acts as a transcription factor.
5) The transcribed mRNA is translated into a specific protein.
The intracellular receptors differ from membrane receptors based on their location. Membrane receptors are usually on the plasma membrane but the intracellular receptors are found inside the cell.
cortisol
Intracellular receptors. They are receptor proteins found on the inside of the cell, typically in the cytoplasm or nucleus
chaperone proteins (chaperonins)
cell surface receptors
All receptors - both intra- and extra- cellular - are extremely specific in their interactions.
chaperone proteins (chaperonins)
It doesn't atropine only acts on muscarinic receptors (it's a competitive antagonist here for ACh), but histamine acts on different receptors (histamine receptors). There is no direct interaction between atropine and histamine receptors
Peter Chidiac has written: 'Cardiac muscarinic receptors and G proteins: mechanism of interaction'
disguising themselves as the male sex hormone, testosterone, which can cause mood swings and other side effects
Mu Receptors are also known as Morphine Receptors. Mu Receptors are located in the Brainstem and Medial Thalamus, they are responsible for supraspinal analgesia, respiratory depression, euphoria, sedation, decreased gastrointestinal motillity and physical dependance. The Subtypes are: Mu1 and Mu2 Mu receptors (as well as Delta and Kappa and even Nociceptin) all these receptors are linked to opiates binding to them. They are members of G-Protien Coupled Receptors. If your new to this sort of thing then i recommend you get onto Wikipedia and start with Mu receptors and learn the pharmacology of Opiates. With MU in particular though the G protein binds to the third intracellular loop of the opioid receptors in the CNS. You should also check out the other spots that opiate receptors are located in the body (i.e. Spinal cord) I hope that i helped you, like i said, i edit alot of articles on Wikipedia.org too so i reccommend you check up on that. Happy Hunting. ----Storm----
Channel linked receptors bind to neurotransmitters. (also called ion channels and ligand gated ion channels) A ligand is the signal molecule i.e the neurotransmitter. Hormones bind to intracellular receptors because hormones are non polar and can cross the cell's plasma membrane. (also called cytoplasmic receptors)