Yes, in the phospholipid bilayer.
Parthapratim Chandaroy has written: 'Control of cell-liposome adhesion and liposome content release by thermally regulating polymer-lipid bilayer interaction' -- subject(s): Drug Delivery Systems, Liposomes, Polyethylene glycol
Guru V. Betageri has written: 'Liposome drug delivery systems' -- subject(s): Drugs, Liposomes, Vehicles
Polymeric micelles are nano-sized colloidal structures formed by the self-assembly of amphiphilic block copolymers in aqueous solutions. They generally consist of a hydrophobic core and a hydrophilic shell, allowing them to solubilize hydrophobic drugs and deliver them to target sites in the body. Polymeric micelles have shown promise as drug delivery systems due to their stability, biocompatibility, and ability to enhance drug solubility and circulation time.
Liposomes are spherical-shaped vesicles that can be created from cholesterol and natural non-toxic phospholipids, and their structure is similar to cell membranes. Liposomes have attracted attention as a carrier system for therapeutically active agents, owing to their unique characteristics, including biocompatibility, self-assembly capabilities, scalability, as well as a broad range of physical and chemical properties. Liposomes have shown great therapeutic potential as carriers for payloads and for delivery to targeted sites, which has led to several liposomal formulations designed for the preclinic and clinical trials, with applications ranging from cancer chemotherapy to gene therapy. Liposomes are used as models for artificial cells. Liposomes can also be designed to deliver drugs in other ways. Liposomes that contain low (or high) pH can be constructed such that dissolved aqueous drugs will be charged in solution (i.e., the pH is outside the drug's pI range). Creative Biolabs provides services for the development of liposome pharmaceutical formulations for the pharmaceutical/biotechnology industry. We have strong and extensive expertise and years of experience in the field of drug delivery and lipid biophysics.
Using Route IL to deliver medication means: to deliver it Intralesional. To inject a drug directly into a skin lesion for faster action of drug and for better results with medication. Tiffany L. Muskegon Michigan
Liposome is a microscopic vesicle composed of a lipid bilayer that can encapsulate drugs, nutrients, or other substances. They are used in drug delivery systems and research applications due to their ability to improve the solubility and bioavailability of poorly soluble compounds and protect their contents from degradation.
An autoinjector is a medical device designed to allow someone to deliver a dose of a particular drug into oneself.
No, but they almost did, Considering that they had developed a super solider drug name D-IX which is a mix of Cocaine, Oxycodone, And methamphetamine. The drug was tested on inmates in concentration camps. The drug allowed the inmates to walk 55 miles with a 20kg pack before collapsing. The hope was that the drug could be used to create a high endurance soldier who could hold back the encroaching enemy. Pleased with the success plans were drawn up to mass-produce the pills and deliver them to all the troops. The war ended before this could happen.
No, this could be harmful to the drug
An ionized drug is generally less lipophilic than its non-ionized form. This is because ionization usually results in the drug having a greater affinity for water rather than lipid-based environments.
Colon targeted drug delivery systems are medicines designed to specifically deliver their effects to the colon. This helps treat things like inflammatory bowel disease.
Micelles are formed from amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts. In aqueous solutions, these molecules arrange themselves into spherical structures with the hydrophobic tails facing inward and the hydrophilic heads facing outward. This organization allows micelles to encapsulate hydrophobic substances, making them important in processes like emulsification and drug delivery. Common examples of molecules that form micelles include surfactants and certain lipids.