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It depends on the drug you are talking about. Drugs with wide margin of safety will not kill you even taken in large amount. Say for example non absorb-able antacids like combination of aluminium hydroxide with magnesium trisilicate. You may eat 10 or 20 tabs and you will not die. There is no reported death with Benzodiazepine derivative and lethal dose was not known for many years. If you take 5 tablets of Phenobarbital 100 mg, you may die. If you take 5 tablets of Paracetamol 650 mg, you may die of liver failure after 3 days. So it depends on individual drug. But never take risk and transfer the patient for emergency medical treatment.

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Q: Could you die of overdose if ingest five pills?
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