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part of an antigen moleculle inside our body. Example: antibody are bound because of epitopes.
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∙ 8y ago
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Is the best definition of epitope?
The immune cells do not recognize an entire immunogen molecule, instead the lymphocytes recognize the unique individual chemical groups or discrete & specific sites having three-dimensional shape on the macromolecules, called epitopes.
Can a antigen have more than one epitope?
yes an antigen can have more than one epitope
What part of the antibody combines with the antigen?
epitope
What Is the difference between antigen binding site and paratope?
Antigen binding site or epitope is a part of an antigen that is recognized by the antibody. Paratope is a part of an antibody that binds on epitope.
Why polyclonal antibody solution is able to precipitate its antigen protein whereas monlclonal antibody solution has hard time to do so?
Polyclonal antibody recognizes several epitopes on the target protein while monoclonal antibody recognizes only single epitope. Sometimes, monoclonal antibodies are not able to precipitate the antigen because the epitope might need to be exposed on the surface of the antigen to be recognized by the antibody. Since the epitope might be hidden and it's a single epitope that is recognized by the monoclonal antibody, the propability of the antibody to reconize the epitope is lower compared with the polyclonal antibody that recognizes several epitopes on the target protein.
What is an autoepitope?
An autoepitope is an autoimmune epitope - a part of a biomolecule which is the target of an immune response.
Why polyclonal antibody tend to have cross-reaction compare to monoclonal antibody?
Polyclonal antibody recognizes several epitopes on the target protein while monoclonal antibody recognizes only single epitope, hence monoclonal antibodies are more specific than polyclonal antibodies. However, sometimes MAbs are not able to precipitate the antigen because the epitope might need to be exposed on the surface of the antigen to be recognized by the antibody. Since some of the epitope might be hidden and it's a single epitope that is recognized by the monoclonal antibody, the propability of the antibody to reconize the epitope is lower compared with the polyclonal antibody that recognizes several epitopes on the target protein this is the reason for the tendency of polyclonal antibodies to have cross-reaction as compared to MAbs. by Victor S Gruezo Jr
In indirect elisa the enzyme liked antibody will attach to?
Another antibody that is attached to the epitope of interest.
Which portion of the antibody binds to the antigen?
Epitope, it is the part of the antigen that is recognized and binds by the antibodies.
What is Antigen binding site of immunoglobulin?
Question is little bit confusing. Anyway I have an answer and hope it make sense to this question. Antibodies binds to a part of an antigen which is known as Epitope.
Is tuberculosis countigous?
If you are asking if TB (tuberculosis) is contagious, the answer is yes. If you are asking if TB is contiguous, the answer is when it is a synthetic viral epitope and is contiguously linked.
What has the author Mee Ling Wong written?
Mee Ling Wong has written: 'Attempts to construct functional epitope-tagged ACTH receptors'
