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What is the effect of constricted arterioles in the glomerular filtration rate?
Constricted arterioles in the glomerulus can lead to a decrease in the glomerular filtration rate (GFR) by reducing the amount of blood flow entering the glomerulus. This can result in decreased filtration of waste and reduced urine production.
What effect does sympathetic stimulation have on the afferent arterioles?
Sympathetic stimulation causes vasoconstriction of the afferent arterioles in the kidneys. This response reduces blood flow into the glomeruli, which can decrease glomerular filtration rate (GFR). The effect is part of the body's mechanism to prioritize blood flow to vital organs during stress or low blood volume situations. Ultimately, this helps conserve water and maintain blood pressure.
What would the kidneys do to maintain GFR if systemic BP increased?
If systemic blood pressure (BP) increases, the kidneys respond by activating autoregulatory mechanisms to maintain the glomerular filtration rate (GFR). This is primarily achieved through the constriction of afferent arterioles, which reduces blood flow into the glomeruli, thus preventing an excessive increase in GFR. Additionally, the juxtaglomerular apparatus may release less renin, further helping to regulate renal blood flow and maintain stable GFR despite fluctuations in systemic BP.
Why would a decrease in plasma protein concentration cause an increase in GFR?
A decrease in plasma protein concentration can reduce the oncotic pressure in the blood vessels, leading to less water reabsorption in the kidneys and more water remaining in the filtrate. This increased water in the filtrate can increase the pressure in the glomerular capillaries, resulting in an increase in glomerular filtration rate (GFR).
How can you decrease the glomerular filtration rate?
gfr is the net results of the balance between hydrostatic pressures &colloid osmotic pressures of intra vascular compartment & within the Bowman's capsule,where the net pressure gradient is towards filtration.i.e. "Net filtration pressure".Any method which will reduce this net filtration pressure will reduce GFR.That can be achieved by increasing the plasma globulin ad albumin level(increase colloid osmotic pressure),hypotension and addition of vasocostrictor at afferent and vasodialtors at efferent tubule(reducing capilary hydrostatic pressure) or obstructing the free flow of urine(increasing Bowman's casular hydrostatic pressure)
What is the effect of reducing afferent arteriole radius on filtration rate?
As the afferent arteriole dilates it exposes the glomerulus to an increased blood pressure, closer and closer to that of the full systemic blood pressure. This increases GFR and Glomerular pressure. -6th Year Medical Student
Is the glomerular filtration rate the same when the efferent arteriole is constricted and dilated?
OLD, INCORRECT ANSWER: Changes in the diameter of the efferent arteriole will either increase (dilation) or decrease (constriction) the blood flow to the glomeruli. An increased flow means a more blood getting filtered over time. NEW, CORRECT ANSWER The 'efferent' arteriole leaves the renal corpuscle. It is easy to remember which direction efferent and afferent things are going by thinking e=exit and a=arrive. If you constrict the efferent arteriole, you actually inhibit blood from leaving the glomerulus, thus increasing the outward hydrostatic pressure pushing fluid into Bowman's capsule and increasing filtration. If you dilate the efferent arteriole, then you reduce pressure in the glomerular capillaries and reduce filtration.
How do you increase your GFR?
To increase your glomerular filtration rate, blood flow needs to be increased to the kidneys and the impaired kidneys function restored. The glomerular filtration rate, of GFR, measures how much blood passes through the glomeruli into the kidneys each minute.
What is the effect of constricted arterioles in the glomerular filtration rate?
Constricted arterioles in the glomerulus can lead to a decrease in the glomerular filtration rate (GFR) by reducing the amount of blood flow entering the glomerulus. This can result in decreased filtration of waste and reduced urine production.
Why ACE inhibitor contraindicated in renal artery stenosis?
In the presence of renal artery stenosis, the resistance in the afferent arteriole is increased. As compensation, Angiotensin II acts to constrict the efferent arteriole in order to achieve adequate profusion of the glomerulus. ACE inhibitors block the conversion of angiotensin I into angiotensin II. Without its vasoconstrictive effect, the efferent arteriole becomes dilated. This leads to a drop in GFR and may lead to renal failure.
In the absence of any regulatory mechanisms what effect do you think an increase in blood pressure would have on glomerular filtration rate?
Generally speaking, it would increase. However, it depends on the reason for the hypertension. For instance, if there is an obstruction or constriction of the renal artery (stenosis, malignancy, etc...) the physiologic affect would to increase the body's BP. This is due to the fact that the obstruction is decreasing hydrostatic pressure to the glomerulus, and transiently decreasing GFR. The body compensates by increasing BP to increase GFR. Patients that present with a renal artery stenosis could in fact be hypertensive with a decreased GFR.
What happens if the diameter of the efferent arteriole is constricted?
When the afferent arteriole is constricted it causes blood to be unable to flow into the glomerulus, overall decreasing hydrostatic pressure and causing the bowman's capsule to decrease filtration.
What releases when the sympathetic nervous system responds to a decrease in glomerular filtration rate?
Increased sympathetic activity causes the afferent arterioles of the renal glomerulus to constrict, thereby reducing blood flow into the glomerulus. Because a decrease in blood flow reduces blood pressure in the glomerulus, which is the driving force for filtration, GFR decreases.
What effect does sympathetic stimulation have on the afferent arterioles?
Sympathetic stimulation causes vasoconstriction of the afferent arterioles in the kidneys. This response reduces blood flow into the glomeruli, which can decrease glomerular filtration rate (GFR). The effect is part of the body's mechanism to prioritize blood flow to vital organs during stress or low blood volume situations. Ultimately, this helps conserve water and maintain blood pressure.
Why would a decrease in plasma protein concentration cause an increase in GFR?
A decrease in plasma protein concentration can reduce the oncotic pressure in the blood vessels, leading to less water reabsorption in the kidneys and more water remaining in the filtrate. This increased water in the filtrate can increase the pressure in the glomerular capillaries, resulting in an increase in glomerular filtration rate (GFR).
What does a GFR of 96 mean?
it is normal gfr level.
What is the effect that aging has on GFR?
Aging typically leads to a gradual decline in glomerular filtration rate (GFR) due to changes in kidney structure and function. This decline is a normal part of aging and is often associated with a decrease in the number of functioning nephrons and reduced renal blood flow. This reduction in GFR can contribute to age-related kidney diseases and changes in medication dosages in older adults.
