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What is a disintegration time apparatus?
For a drug to show maximum availability in the body it must be in solution form. So as a first step, the tablets that we take in, should break down to smaller particles or granules.This breaking up process is known as disintegration. disintegration is an important parameter of the tablet. It is determined with an apparatus described
What is the cobb value for cast coated paper?
what is the cobb test value for coated test liner
Reason for taking900ml of water as disintegration medium in disintegration test?
Taking 900ml of water as the disintegration medium in a disintegration test is commonly used to simulate the conditions of the stomach where the dosage form is expected to disintegrate. This volume is considered sufficient to provide the necessary agitation and dissolution properties needed for the test. It also helps ensure reproducibility and accuracy in the disintegration test results.
What tablet is dropped into a test tube of urine to test glucose?
A glucose tablet is usually dropped into a test tube of urine to test for glucose. The tablet contains a substance that reacts with glucose in the urine, causing a color change that indicates the presence of glucose.
Explain why H2S production test would be diagnostically significant for isolating enteric organisms?
why the H2S production test would be diagnostically significant?
What is Normalized Test?
Widal test is a serological test used to detect enteric fever by using agglutination rection of antibodies present in the serum of typhoid patient and o-somatic and H-flgellar antigens.
Why you do friability test for tablet?
bcoz of coating. And for transport
Can you get the impossible test space on Android tablet?
Yes
What is the dissolution test for aspirin tablet?
acetate buffer pH4.5
Why some tablets are dispersible?
Fast dispersible tablets disintegrate either rapidly in water, to form a stabilized suspension, or disperse instantaneously in the mouth to be swallowed without the aid of water. A direct compression method was used to prepare these two types of tablets containing coated ibuprofen as a high dosed model drug. The properties of the water dispersible tablet, such as porosity, hardness, disintegration time and increase in viscosity after dispersion, were investigated. The selected tablet formulation, containing 26% galactomannan and 5% crospovidone, disintegrates before the galactomannan starts to swell. These tablets disperse in water within 40 s and show a crushing strength of 95 N. To develop an orodispersible tablet, a rotatable central composite design was applied to predict the effects of the quantitative factors mannitol and crospovidone as well as compression force on the characteristics of the tablet. Special emphasis was paid to the development of a wetting test, replacing the normal disintegration method. An optimum tablet formulation, containing 34% mannitol and 13% crospovidone, provides a short wetting time of 17 s and a sufficient crushing strength of 40 N. In conclusion, fast dispersible tablets with acceptable hardness and desirable taste could be prepared within the optimum region.
What is the principle of disintegration test apparatus?
basic principal of dissolution run as per individuala monograph and know the % of active drugs in sample
Is staphylococcus aureus negative for the methyl red test?
Yes, Staphylococcus aureus is negative for the methyl red test due to its inability to produce stable acids from glucose fermentation. This distinguishes it from other enteric bacteria that are positive for the methyl red test.
