0
For a drug to show maximum availability in the body it must be in solution form. So as a first step, the tablets that we take in, should break down to smaller particles or granules.This breaking up process is known as disintegration. disintegration is an important parameter of the tablet. It is determined with an apparatus described
What else can I help you with?
What is the principle of disintegration test apparatus?
basic principal of dissolution run as per individuala monograph and know the % of active drugs in sample
How does roots cause disintegration?
Roots cause disintegration by growing into small cracks in rocks or structures and exerting pressure as they expand, leading to physical breakup of the material. Additionally, roots can release chemicals that break down the composition of the material they are growing on, causing further disintegration over time.
Reason for taking900ml of water as disintegration medium in disintegration test?
Taking 900ml of water as the disintegration medium in a disintegration test is commonly used to simulate the conditions of the stomach where the dosage form is expected to disintegrate. This volume is considered sufficient to provide the necessary agitation and dissolution properties needed for the test. It also helps ensure reproducibility and accuracy in the disintegration test results.
Why are some isotopes half-lifes?
Each isotope has a different rate of radioactive disintegration characterized by the half-life, the time necessary to reduce by half the number of atoms.
Why radioactivity is considered as a first order reaction?
Radioactivity is the disintegration of the substance by its own. This means disintegration depends only on one reactant concentration i.e.,on itself. So this is a first order reaction.
What is the principle of disintegration test apparatus?
basic principal of dissolution run as per individuala monograph and know the % of active drugs in sample
What is disintegration time of tablet?
dissintigration time is the time that required to convert solid tablet in to granlues.
President of the Russian Republic at the time of the disintegration of the Soviet Union?
Boris Yeltson
What are the disintegration times of coated and uncoated tablets?
The disintegration time of coated tablets is typically longer compared to uncoated tablets due to the additional layer of coating that needs to dissolve before the tablet can disintegrate. Coated tablets are designed to release the medication gradually over time, which can affect the disintegration process. Uncoated tablets, on the other hand, disintegrate more quickly as they do not have an additional barrier to dissolve. The specific disintegration times can vary depending on the formulation of the tablet and the conditions in which it is tested.
What is vicat apparatus used for?
vicats apparatus is used for initial setting time of cement.
When was The Disintegration Machine created?
The Disintegration Machine was created in 1929.
When was The Disintegration Loops created?
The Disintegration Loops was created in 1982.
What can make the structure fail over time?
Rust, disintegration of materials, etc. etc.
What is the disintegration time of film coated tablet?
The disintegration time of a film-coated tablet can vary depending on the formulation and the specific film coating used. Generally, film-coated tablets are designed to disintegrate in the stomach or intestines within a few minutes to one hour after ingestion. The disintegration time is determined during the tablet development process to ensure proper drug release and absorption.
How does roots cause disintegration?
Roots cause disintegration by growing into small cracks in rocks or structures and exerting pressure as they expand, leading to physical breakup of the material. Additionally, roots can release chemicals that break down the composition of the material they are growing on, causing further disintegration over time.
What is disintegration time for enteric coated tablets?
The time of disintegration is basically based by the pharmaceuticals keeping in mind the timing of the digestive system so that the medicine is administered at the correct location,throat, stomach,upper or lower intestines etc. to have the necessary effect.
Definition of disintegration constant?
The disintegration constant is the fraction of the number of atoms of a radioactive nuclide which decay in unit time; is the symbol for the decay constant in the equation N = Noe^-t, where No is the initial number of atoms present, and N is the number of atoms present after some time (t).
