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No, Cancer cells do not realize that they are becoming invasive and therefore keep dividing and eventually metastasize.
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As a patch of scraped skin heals the cells fill in the injured area but do not grow beyond that This is an example of density-independent inhibition. density-dependent inhibition. anchorage indepe?
Density-dependent inhibition
What is a density-dependent inhibition?
A density dependent inhibition is when cells become more and more numerous, the required growth factors and nutrients become insufficient making cell growth difficult.
Observations of cancer cells in culture support the hypothesis that cancer cells?
a) do not exhibit density-dependent inhibitionb) produce molecules that inhibit the growth factors required for cell divisionc) exhibit anchorage dependenced) spend the majority of their time in the G(0) phasee) do all of the aboveANSWER: a) do not exhibit density-dependent inhibition
You are asked to culture an unidentified sample of animal tissue you notice that cells seem to fail to exhibit density-dependent inhibition the source of this tissue sample is most likely?
Mostly these are non epithelial cells...
What is a inhibition?
A density dependent inhibition is when cells become more and more numerous, the required growth factors and nutrients become insufficient making cell growth difficult.
What is the phenomenon observed in normal animal cells that causes them to stop dividing when they come into contact with one another?
density dependent inhibition
What are density dependent inhibition and anchorage dependence and how do they relate to cancerous cells?
Basically, regular cells, otherwise known as somatic cells, abide by these two inhibitors. A normal, healthy somatic cell will grow and divide until it meets an impassible barrier, such as the edge of a petri dish. This is density dependent inhibition. Such cells also have to be touching some kind of surface in order for the cell to begin to divide. This is known as anchorage dependency. Both of these relate to cancer cells as these cell do not follow these two rules. The cells will continue to divide until they are killed, as they do not follow any of these inhibitors.
What is contact inhibition in cells?
Cancer cells do NOT exhibit contact inhibition, meaning that when they come in contact with another cell, the do NOT stop growing.
What is the cases represented as the phenomenon of contact inhibition?
Contact inhibition helps keep cells growing in a layer that is the width of one cell. Cancer cells lose this property when they form.
What can you do to stop a cell from continuing to reproduce?
You really can't! The body has their own rules, and they make the rules of cell division. You can't stop cell division.AnswerThe answer above is incorrect. Although the body may have its own rules, there are some rules we understand well enough to disrupt in order to halt the cell cycle completely. Additionally, there are many many many things that can go wrong that could affect the cell cycle. One such process that should be familiar is cancer. However, cancer has the opposite effect (as it will speed up mitosis exponentially). But cells stop mitosis naturally. Some nerve and muscle cells as well as multinucleated cells are at the G0 phase of mitosis, where they no longer reproduce. Without going too deep into the specifics, there are a number of enzymes and molecules that are required so the cell can proceed to the next phase of the cell cycle, called checkpoints. If the molecules simply aren't there or an inhibitor is present, the cell will exit the cell cycle into G0. This can and does happen naturally, but it could also be induced.In addition, a conflagration of functions is needed to make reproduction occur. If any one of those fails -- say the cytoskeleton or centrioles -- then division will not take place. There are also external factors such as density dependent inhibition or presence of a substrate. If there are too many cells around the cell in question, it will not grow or divide (this is called density-dependent inhibition, because it depends on the density of cells around it. Cancer cells notably don't exhibit density-dependent inhibition). Some cells also need a substrate (or surface) to attach to before growing or dividing. If there isn't one present, it may not proceed through the cell cycle (also not an issue for cancer cells).Some links are provided below for more information.
How are cancer cells and contact inhibition connected?
Normal cells stop growing and reproducing once their plasma membrane comes into contact with that of another cell. Cancer cells don't. They continue to grow into other cells, taking over and often destroying the other cells, creating a tumor.
What do normal cells do when they come into contact with other cells?
Contact Inhibition
