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My Mother has been on Depakote (treating agitation due to dementia) for at least 2-3 years. She was recently taken off of this drug. I was under the impression that she would have to be weaned from this drug, but was told that it was not necessary. So far, so good. I think she has reached a point in the disease that these drugs are no longer necessary. She seems a little more with it and hopefully, not as sleepy. This may also be a reason why she is always so cold, but she is also diabetic.

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Q: Do patients receiving depakote to manage agitation due to dementia need to have gradual dose reductions?
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