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Although Depakote is sometimes used by people as a substitute for street drugs, this is not that common. It works by slowing the brain's activity. It does not repair neurotransmitters - neurotransmitters are chemicals that help brain cells "talk" to each other.

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No, it is impossible to get high off of Depakote, as all it does is repair damaged Neurotransmitters in the brain.

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Q: Do you get high on Depakote?
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