No, if you went from Nashville to Memphis you would be going in the complete opposite direction from the Smokey mountains. Nashville is in the very middle section of the state of Tennessee. Going from Nashville to Memphis would take you a straight shot west. The Smokey mountains are nearly a straight shot east of Nashville. So from Nashville you would actually go toward Knoxville to get to the Smokey mountains. Eventually you would vear north just slightly.
I-75 North/South through Knoxville and Chattanooga I-65 North/South through Nashville I-40 East/West through Memphis Nashville and Knoxville I-55 North/South through Memphis I-81 North/South between Knoxville and Johnson City
I-75 North/South through Knoxville and Chattanooga I-65 North/South through Nashville I-40 East/West through Memphis Nashville and Knoxville I-55 North/South through Memphis I-81 North/South between Knoxville and Johnson City
The driving distance between Nashville TN and Pigeon Forge TN is 213 miles. Pigeon Forge is in the eastern area of Tennessee near the Great Smokey Mountains National Park. Nashville is in central Tennessee along Interstate 40. If you are traveling along Interstate 4o from western U.S. states you will pass through Nashville. However, if you are travelling from east coast states you will not pass through Nashville.
If you are traveling northward through Arkansas, Missouri, and Iowa, you would pass through the Ozark mountains, which form the southern edge of the Ozarks.
Driving from Raleigh to Knoxville you would drive on Interstate 40 and pass through the Great Smokey Mountains. They are part of the Blue Ridge Mountains which are part of the larger Appalachian Mountains.
Nashville TN is in the South Region. Bismarck IL is in the Midwest Region. Traveling from Nashville to Bismarck you would travel through the South and Midwest Regions.
It runs south from Cincinatti Ohio through Covington to Lexington and then through the Cumberland Mountains and Plateau on its way to Knoxville Tennessee.
If you go I-26 west to I-81 south I-40 west through Knoxville, its like 295-300 miles
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Just from driving through it, I would say mostly rural. There is Knoxville on the Eastern border and Nashville and Memphis at the West, but not much in between that is Urban.
It is 758 miles via I-40 according to Google Maps. That route takes you through Nashville, Memphis, Little Rock and Texarkana.