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No, you do not need to have a lumbar puncture (also called a spinal tap) to have a diagnosis of definite MS.

The clinical diagnosis of MS is made when the patient has two clinical events separated by space and time. Separation of space means having symptoms in different bodily systems; for example, a vision change and a motor control issue. Separation of time is most universally regarded as a difference of about six months. Additionally, there must be no other cause for these events.

MS is a diagnosis of exclusion. This means that you have to exclude everything else that could potentially be causing those symptoms until all you are left with is MS. This is because every symptom which can appear with MS can also appear in other diseases and conditions. This is why MS is often called "the Great Imitator."

The lumbar puncture is part of the "body of evidence" which is used to confirm a diagnosis of MS. Used more frequently these days is a high-field (1.5T or 3T) MRI of the brain. These tests, along with meeting the clinical standards listed above, can lead to a diagnosis of MS.

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Q: Do you need to have lumbar puncture for certain to diagnose ms?
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