Without B12, red blood cell production is greatly reduced
Red blood cells
Yes, a high dose of B12 can affect it. I had irregular menstruation symptoms, sometimes half a year and longer without menstruating, and -always- after a high dose of B12 (oral, not injected) the menstruation started a few hours later. This is probably caused by something called intrinsic factor - stomach cells that produce intrinsic factor are destroyed or missing, without them you can't absorb B12, no matter if your diet includes more or less B12. Only very high doses may get through (or injected B12), these high doses are not present in ANY food. As soon as your B12 storage is emptied (B12 can be stored in the body for 5-12 years or so), symptoms of B12 deficiency occur, it leads to pernicious anaemia, means that the production of red blood cells is defect, blood cells won't divide any more, you start to have less, but huge red blood cells, since they are not divided. In this environment your menstruation probably stops due to the deficiency of healthy red blood cells. My conclusion is that a very high dose of B12 probably leads to a sudden rush of blood cells, and this may start the menstruation, even after it has stopped for a very long time. Don't forget to supplement iron, and folic acid together with B12 - since the production of blood cells depends on them. For that reason a high dose of B12 may lead to an iron and folic acid deficiency, if not supplemented, they are all used up to build the new blood cells.
Folate and vitamin B12 primarily functions in cell regeneration and the synthesis of red blood cells.
Vitamin B12
They are cofactors in the synthesis of DNA so their function resides in the reproduction and maduration of blood cells. B6 and B12 deficit can lead to anemia, leukopenia, thrombocytopenia or pancytopenia, that is low red blood cells, low white blood cells, low platelets or low blood cells in general.
B12/folate, Vitamin C, Copper,
You can become anemic if you have a B12 deficiency. The vitamin is needed to make hemoglobin for your red blood cells.
LDH enzyme (subtype 4H) is very abundant in red blood cells and heart muscle. In vit B12 deficiency there is high destruction of red cells in the bone marrow and in the blood vessels. As RBCs ruptures they release their inner content into the blood stream. So that's how LDH goes up in the blood.
They actually have no affect on each other. Blood is composed of approximately 44% red blood cells, about 1% of white blood cells and platelets, and 55% plasma.
Thalassemia - which affect the red blood cells as oppose to white blood cells in leukemia.
B12 is vitamin B12, also called cobalamin. The main function of cobalamin is aiding in brain and nervous system function. Cobalamin is water-soluble and is used to make red blood cells.
Vitamins b6 and b12 support your bodyâ??s metabolism and produces neurotransmitters and red blood cells. Vitamins b6 and b12 are seldom a deficiency, as they are found in a multitude of foods.