The presence of an omphalocele often occurs with other birth defects
Prenatal screening can detect approximately 85% of abdominal wall defects. Gastroschisis and omphalocele are usually diagnosed by ultrasound examinations before birth
Omphalocele is a congenital condition caused by a failure of the abdominal wall to close properly during fetal development, resulting in the intestines or other abdominal organs protruding through the abdominal wall at the base of the umbilical cord. The exact cause is often unclear, but it is associated with genetic factors, maternal conditions, and certain environmental influences. Omphalocele can occur as an isolated defect or in conjunction with other congenital anomalies, such as chromosomal abnormalities.
performed to repair the omphalocele defect in which all or part of the bowel and other internal organs lie on the outside of the abdomen in a hernia (sac).
Congenital defects of the lungs, omphalocele, fetal gastroschisis, bowel obstructions, hypoplastic left heart syndrome, X-linked severe combined immunodeficiency syndrome, spina bifida.
There are no non-surgical alternatives to omphalocele repair
omphalocele (protrusion of part of the intestine through the abdominal wall)
a surgery performed to correct one of two birth defects of the abdominal wall: gastroschisis or omphalocele. Depending on the defect treated, the procedure is also known as omphalocele repair/closure or gastroschisis repair/closure
DefinitionAn omphalocele is a birth defect in which the infant's intestine or other abdominal organs stick out of the belly button (navel). In babies with an omphalocele, the intestines are covered only by a thin layer of tissue and can be easily seen.An omphalocele is a type of hernia. Hernia means "rupture."See also:Omphalocele repairUmbilical herniaCauses, incidence, and risk factorsAn omphalocele develops as a baby grows inside the mother's womb. The muscles in the abdominal wall (umbilical ring) do not close properly. As a result, the intestine remains outside the umbilical cord.Approximately 25 - 40% of infants with an omphalocele have other birth defects. They may include genetic problems (chromosomal abnormalities), congenital diaphragmatic hernia, and heart defects.SymptomsAn omphalocele can be clearly seen, because the abdominal contents stick out (protrude) through the belly button area.There are different sizes of omphaloceles. In small ones, only the intestines stick out. In larger ones, the liver or spleen may stick out of the body as well.Signs and testsPrenatal ultrasounds often identify infants with an omphalocele before birth. Otherwise, a physical examination of the infant is enough for your health care provider to diagnose this condition. Testing is usually not necessary.TreatmentOmphaloceles are repaired with surgery, although not always immediately. A sac protects the abdominal contents and allows time for other more serious problems (such as heart defects) to be dealt with first, if necessary.To fix an omphalocele, the sac is covered with a special man-made material, which is then stitched in place. Slowly, over time, the abdominal contents are pushed into the abdomen.When the omphalocele can comfortably fit within the abdominal cavity, the man-made material is removed and the abdomen is closed.Sometimes the omphalocele is so large that it cannot be placed back inside the infant's abdomen. The skin around the omphalocele grows and eventually covers the omphalocele. The abdominal muscles and skin can be repaired when the child is older to achieve a better cosmetic outcome.Expectations (prognosis)Complete recovery is expected after surgery for an omphalocele. However, omphaloceles often occur with other birth defects. How well a child does depends on which other conditions the child also has.If the omphalocele is identified before birth, the mother should be closely monitored to make sure the unborn baby remains healthy. Plans should be made for careful delivery and immediate management of the problem after birth. The baby should be delivered in a medical center that is skilled at repairing omphaloceles. The baby's outcome is improved if he or she does not need to be taken to another center for further treatment.Parents should consider screening their unborn baby for other genetic problems that are associated with this condition.ComplicationsDeath of the intestinal tissueIntestinal infectionCalling your health care providerThis problem is diagnosed and repaired in the hospital at birth. After returning home, call your health care provider if the infant develops any of these symptoms:Decreased bowel movementsFeeding problemsFeverGreen or yellowish green vomitSwollen belly areaVomiting (different than normal baby spit-up)Worrisome behavioral changesReferencesTownsend CM, Beauchamp RD, Evers BM, Mattox KL. Sabiston Textbook of Surgery, 17th ed. St. Louis, M0: WB Saunders; 2004:2116-2117.Ledbetter DJ . Gastroschisis and omphalocele. Surg Clin North Am. April 2006; 86(2): 249-60, vii.
The omphalocele repair is a surgical procedure performed under general anesthesia
An omphalocele is a defect that can be viewed on sonogram during an ultrasound performed while the mother is pregnant
None of the defects occur after birth, they all develop in the womb. They continue to exist for the entire life of the person, of course.
Within a crystal there are point defects and line defects; point defects are missing or extra lattice points within the crystal lattice (vacancies or interstitials), line defects may be due to an 'extra' half lattice plane within the crystal. The end of a line defect plane is known as an edge dislocation, screw dislocations occur where part of a crystal is displaced over one lattice direction and is therefore twisted. Dislocation loops can occur where an edge and a screw dislocation intersect.