It messes up your sinuss (making your nose constantly run), it makes your heart race faster, and it messes up your body. Just say NO to ALL DRUGS!!!! Your life is better off that way! Also, it makes you like Tim!!
The most extensively studied effect of cocaine on the central nervous system is the blockage of the dopamine transporter protein. Dopamine transmitter released during neural signaling is normally recycled via the transporter; i.e., the transporter binds the transmitter and pumps it out of the synaptic cleft back into the pre-synaptic neuron, where it is taken up into storage vesicles. Cocaine binds tightly at the dopamine transporter forming a complex that blocks the transporter's function. The dopamine transporter can no longer perform its reuptake function, and thus dopamine accumulates in the extracellular space (synaptic cleft). This results in an enhanced and prolonged post-synaptic effect of dopaminergic signalling at dopamine receptors on the receiving neuron. Prolonged exposure to cocaine, as occurs with habitual use, leads to homeostatic dysregulation of normal (i.e. without cocaine) dopaminergic signaling via downregulation of dopamine receptors and enhanced signal transduction. The decreased dopaminergic signalling after chronic cocaine use may contribute to depressive mood disorders and sensitize this important brain reward circuit to the reinforcing effects of cocaine (e.g. enhanced dopaminergic signalling only when cocaine is self-administered). This sensitization contributes to the intractable nature of addiction and relapse. Dopamine-rich brain regions such as the ventral tegmental area, nucleus accumbens, and prefrontal cortex are frequent targets of cocaine addiction research. Of particular interest is the pathway consisting of dopaminergic neurons originating in the ventral tegmental area that terminate in the nucleus accumbens. This projection may function as a "reward center", in that it seems to show activation is response to drugs of abuse like cocaine in addition to natural rewards like food or sex. While the precise role of dopamine in the subjective experience of reward is highly controversial among neuroscientists, the release of dopamine in the nucleus accumbens is widely considered to be at least partially responsible for cocaine's rewarding effects. This hypothesis is largely based on laboratory data involving rats that are trained to self-administer cocaine. If dopamine antagonists are infused directly into the nucleus accumbens, well-trained rats self-administering cocaine will undergo extinction (i.e. initially increase responding only to stop completely) thereby indicating that cocaine is no longer reinforcing (i.e. rewarding) the drug-seeking behavior. Cocaine also blocks sodium channels, thereby interfering with the propagation of action potentials; thus, like lignocaine and novocaine, it acts as a local anesthetic. Cocaine also causes vasoconstriction, thus reducing bleeding during minor surgical procedures. The locomotor enhancing properties of cocaine may be attributable to its enhancement of dopaminergic transmission from the substantia nigra. Recent research points to an important role of circadian mechanisms and clock genes in behavioral actions of cocaine. Because nicotine increases the levels of dopamine in the brain, many cocaine users find that consumption of tobacco products during cocaine use enhances the euphoria. This, however, may have undesirable consequences, such as uncontrollable chain smoking during cocaine use (even users who do not normally smoke cigarettes have been known to chain smoke when using cocaine), in addition to the detrimental health effects and the additional strain on the cardiovascular system caused by tobacco. In addition to irritability, mood disturbances, restlessness, paranoia, and auditory hallucinations, crack can cause several dangerous physical conditions. It can lead to disturbances in heart rhythm and heart attacks, as well as chest pains or even respiratory failure. In addition, strokes, seizures and headaches are common in heavy users. Cocaine can often cause reduced food intake, many chronic users lose their appetite and can experience severe malnourishment and significant weight loss.
There are many things a drug can do to the body, but it seems that the
"stimulant" drugs….drugs like cocaine and amphetamine ("speed")…do more
than their share of bodily harm!
Mainly, cocaine makes you breathe heavier, harder and forces your heart to
pump much faster. Your pupils dilate, your blood pressure goes through the
roof, and your body temperature rises. This kind of over-activity can
cause some serious permanent damage if the drug is taken over a period of
time….it's not terribly uncommon for a frequent user to suffer heart
attacks or respiratory failure, partly because of all of this
wear-and-tear!
Other effects of taking cocaine for a long time include "stimulant
psychosis", a permanent disorder that closely resembles schizophrenia.
Paranoia and tactile hallucinations (hallucinations that you feel…..like
bugs crawling on and/or under your skin). Other problems that come from
cocaine use include irritability, restlessness, anxiety, insomnia,
and--sometimes--seizures.
Health problems from bad circulation and poor nutrition are rather common,
too. The latter one is partly because stimulants--like cocaine--are also
appetite suppressants. Cocaine users don't eat much, so their nutritional
intake really suffers.
Lots of people sniff cocaine, and it's a serious irritant! People who use
cocaine a lot this way eventually wear down their mucous membranes and end
up with serious nasal problems! Smoking it will obviously cause
respiratory disorders, on top of the stimulant effect that I mentioned
before, and injecting any drug is a very common way of transmitting
blood-borne diseases like HIV, and hepatitis.
As you can see, cocaine can do a lot of damage to a person's body…not just
by the drug itself, but by the things you may do while under it's
influence, or the way it is taken into the body. There's more information
on this (and other drugs) at this site check it out!
First and foremost, cocaine affects the brain and central nervous system. By stimulating areas deep in the brain, it initially causes the brain to produce powerful sensations of pleasure. However, interfering with the normal function in these areas produces sensational disfunction and physical addiction usually accompanied by serious long-term psychological disturbances. The cardiovascular system is affected. Cocaine can cause heart attacks and strokes. When in use it increases one's heart rate and sky rocket's one's blood pressure. It also suppresses appetite which can cause malnutriton. Cocaine also has damaging effects on the respiratory system, the gastrointestinal system, and the renal system. The renal system is a serious concern in even moderate cocaine use, since damage to the kidneys is accumulative and usually irreversible.
Cocaine affects the body by, going through your veins and messing with your blood stream. It can cause damage to the brain and blood cells
HELLO IM DAFFY DUCKCAN I HELP YOU ANSWER YOURQUESTION? WHY YES IT DOESAFFECT THOSE AREAS AND HOWDO I KNOW THAT? WELL I AM DAFFY DUCK!REMEMBER KIDSDAFFY DUCK TO THE RESCUE
it can Make your teeth fall out, your bones become weaker, and your skin looks like if it was burned
It affects your penis you get a massove erection thays why ots so addicting...
Yes it does because coke has certain bad acid's and ingredients it contains caffeine And that's bad for you.
Its good for you
never!
it affects the brain most
Cocaine enters the body by the person snorting, injecting, or in its synthesized form (crack-cocaine) smoking. the drug enters through the blood vessels in either the sinus tissue, lungs, or directly to the blood. It then is carried through the blood stream and around the body, makes a trip through the brain, and down to your liver, where it is processed and excreted through your urine. Cocaine takes no longer than a 0.7th of a second between entering the body and feeling the euphoric effects.
If you smoke freebase cocaine, it releases methylecgonidine into the user's body, which can be damaging to heart, lungs, and liver.
The organ systems of the body in alphabetical order are:Cardiovascular/circulatoryDigestiveEndocrineIntegumentaryLymphaticMuscularNervousReproductiveRespiratorySkeletalUrinary
Cocaine blocks the removal of Dopamine from the synaptic cleft, causing the existing Dopamine to bind again and again, overstimulating the cell. At first the cell just fritzes out- producing the high. But then, to counteract the extra stimulus, the body starts to remove Dopamine receptors. That's why it takes an ever increasing amount of cocaine (or meth or whatever stimulant you choose) to produce a similar high.
central nervous system
it affects the brain most
It will affect your lungs and breathing.
As is progresses, bulimia can affect virtually all of the systems in the body.
everything
It delivers blood to the other systems.
Your teeth and your gums; nervous and excretory systems.
Anorexia can (and does) affect all systems and parts of the body.
the lymphatic system
Yes
circulatory
The Nervous System.