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if an indivigual has a dominent allele for a disease he/she is an affected individual.
Huntington's disease is caused by a dominant allele
It could happen in two main mechanisms: 1) the allele responsible for the disease is recessive and so each of the parents are healthy portators of the allele (heterozygous), and all the sons which are homozygous for the allele (i.e. have two copies of the allele), with a frequency of 1:4, will be affected by disease, but not the others (heterozygouses and homozygouses for the good allele or wild type). 2) the mutation responsible for the disease (that acts in a dominant manner) is not present in any of the parents but happens only during the formations of gametes, and so will be transmitted to the son. There are also other mechanisms that are less frequent and more difficult to explain in a few words.
Yes, Huntington's disease is autosomal dominant with high penetrance. Every individual who inherits the allele gets the disease.
DNA sequencing
Huntington's Disease.
Huntington's Disease
Huntington's Disease
The allele that causes Huntington's disease is dominant. This means that there only needs to be one present in the gene for it to show in the person's phenotype.
Men- XgY(g here if the y chromesome carries the allele) Women-XgXg
a carrier
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