A high globulin count is caused by chronic infections, chronic inflammation as in rheumatoid arthritis and autoimmune syndromes such as lupus, multiple myeloma and Waldenstrom macroglobulinemia, reports Patient. Liver cirrhosis and nephrotic syndrome can cause an elevated globulin serum ratio by decreasing serum albumin levels
Nephrotic syndrome can be caused by a number of different diseases. The common mechanism which seems to cause damage involves the immune system. For some reason, the immune system seems to become directed against the person's own kidney.
Nephrotic syndrome is a group of symptoms including protein in the urine (more than 3.5 grams per day), low blood protein levels, high cholesterol levels, high triglyceride levels, and swelling. Nephrotic syndrome is caused by various disorders that damage the kidneys, particularly the basement membrane of the glomerulus. This immediately causes abnormal excretion of protein in the urine.
Multiple myeloma begins when the genetic material (DNA) is damaged during the development of a stem cell into a B-cell in the bone marrow. This causes the cell to develop into an abnormal or malignant plasmablast.
Fat in the urine (lipiduria) is a symptom of the nephrotic syndrome - a kidney condition that cause loss of protein (and some lipoproteins) in the urine.!
Either uninary tract infection,presence of calcium salts or light-chain diseases as in multiple myeloma.
It idicates inflamation or infection.
There are several different things that can cause a person to have low protein levels. Some of these causes include bleeding, liver disease, malnutrition, nephrotic syndrome, and agammaglobulinemia.
Geraldine Ferraro was diagnosed with multiple myeloma, a form of blood cancer that causes bone tumors, in 1998. She died of complications from the disease on March 26, 2011.
Heart disease Cancer Accidents (unintentional injuries) Chronic lower respiratory diseases Stroke (cerebrovascular diseases) Alzheimer’s disease Diabetes Influenza and pneumonia Nephritis, nephrotic syndrome, and nephrosis Intentional self-harm (suicide)
Deletion Mutation causes DiGeorges Syndrome.
If the mother smoked while pregnancy it leads to infant death syndrome.