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The absolute refractory period. This period occurs after the action potential has been initiated and is a result of inactivation of the sodium channels. These sodium channels would normally open up to allow sodium influx into the cell during an action potential. The absolute refractory period occurs during an ongoing action potential and is the period in which a subsequent action potential absolutely cannot be generated.This should not be confused with the relative refractory period which occurs immediately following the absolute refractory period (during membrane hyperpolarization). During this period a subsequent action potential is possible, but more difficult to attain.
Relative refractory period
The relative refractory period is the time during which the generation of an action potential is impossible no matter the strength of the stimulus
Threshold stimulus
In a negative feedback loop, the output of the system decreases the intensity of the stimulus.
the neuron is unable to respond to a stimulus of any intensity
After the generation and propagation of an action potential along a neuron, the cell becomes depolarized to the point where there is no potential for further signaling until the cell re-polarizes through the action of ion pumps. This very brief period is called the refractory state.
Absolute Refractory Period:It is the interval during which a second action potential absolutely cannot be initiated, no matter how large a stimulus is applied.ORAfter repolarization there is a period during which a second action potential cannot be initiated, no matter how large a stimulus current is applied to the neuron. This is called the absolute refractory period, and it is followed by a relative refractory period, during which another action potential can be generated
refractory period is the interval between action potential , the absolute refractory period is the period in which second action potential can not be initiated but in relative refractory period the second action potential can be initiated by the more strong stimulus.
In absolute refractory period, none of channels are reconfigured, so that second active potential cannot be generated no matter how large the stimulus current is applied to the neuron. In contrast, in relative refractory period, some but not all of channels are reconfigured, another action potential can be generated but only by a greater stimulus current thatn that originally needed.
Absolute refractory period
Absolute refractory period (time which local area of the membrane has surpassed the threshold potential and will not respond to any stimulus).
Absolute refractory period (time which local area of the membrane has surpassed the threshold potential and will not respond to any stimulus).
Muscle tetany occurs in muscles without absolute refractory period. The stimulus for contraction comes before the preceding contraction/relaxation is over leading to multiple action potentials without a refractory period. It does not occur in cardiac muscle because it has absolute refractory period during which the muscle cannot be excited, thus making tetany impossible
The absolute refractory period. This period occurs after the action potential has been initiated and is a result of inactivation of the sodium channels. These sodium channels would normally open up to allow sodium influx into the cell during an action potential. The absolute refractory period occurs during an ongoing action potential and is the period in which a subsequent action potential absolutely cannot be generated.This should not be confused with the relative refractory period which occurs immediately following the absolute refractory period (during membrane hyperpolarization). During this period a subsequent action potential is possible, but more difficult to attain.
-The effective refractory period is the time in which the cell is incapable of responding to a second stimulus between the phases of 0-3.5, while the relative refractory period is the time in which the cell is making preparations to receive stimulus between phase 3.5-4.
Relative refractory period