lack of immunities
Frank Fritz is sick with Crohn's Disease. Frank is part of the duo on American Pickers. He has said he had the disease for over a quarter of a century.
The "Black Death" or bubonic plague swept Europe in the 14th Century, over 200 years before Shakespeare's time. Although plague outbreaks were common in the 16th and 17th century, the disease had mutated and was at that time "pneumonic plague" which had different symptoms. One disease that swept Europe during the sixteenth century was Syphilis, a sexually transmitted disease which sailors brought back from the Americas.
Smallpox qualifies as such. It killed off more than 25-50 million people, leaving Mexico with only 1-2 million by 1550.
Probably, prevailing had less to do with things that people can be proud of, than the effects of bringing a different outlook, technology and immunity to the native peoples, who were living a stone age life. Guns. Disease. Treaties that the Indians understood as lending the land, not selling it.
Disease , this is the right answer for apex (:
it was a disease palgue from the old century
Infectious disease was the leading cause of death prior to the 20th century !:]
Harsh climates, disease and hostile Native-American tribes are the main factors that slowed or inhibited settlement among Florida and Mexico until the 19th century.
Disease
The spread of disease
Disease , this is the right answer for apex (:
One was disease (: