How are drugs absorbed and metabolized?

Answer 1

This entirely depends on the drug itself, some drugs can be absorbed thru the skin, such as lsd, novacain, and a few others, but most require injestion and contact with a mucus membrane, such as nasal membranes, mouth, stomach, etc... Differant drugs will pass thru them at differant rates, some drugs can be put up the nose, such as cocain or otrivin, others need time in the stomach or intestines, and still others will not be active unless injected. The metabolism of drugs is just as varied, some drugs are destroyed by stomach acid or enzymes, others need them to be active, some are active in their normal state and will be metabolised instantly, others need to be converted into an active chemical in the blood or liver. Drugs can either act on the body or the mind, either by affecting cells, or activating neural receptors. In order to answer this question effectivly, a specific drug would have to be named, since every single drug acts differantly in the body.

Answer 2

Drugs can be absorbed by various routes such as orally, intravenously, or topically. Once absorbed, drugs are metabolized mainly in the liver through processes like oxidation, reduction, and hydrolysis. Metabolites are then excreted from the body via urine, feces, or breath.

Answer 3

Water soluble drugs are not readily absorbed. But through the very large surface area of the intestine, the water soluble drugs are also absorbed, eventually.