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These patients as with any other patients suffering from a transfusion dependant anaemia could be at serious risk of iron overload. This is a serious side effect of transfusion and can shorten lives significantly if not addressed. It can also exacerbate some of the symptoms of Sickle Cell Anaemia. So, the way that this is managed is with a drug called an Iron chelator. There are two to choose from at the moment, and I am sure the most preferable would be a drug which is taken once a day as a tablet dispersed in water (the other option is a 8-12hour infusion every day).

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16y ago

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