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Without the proper enzymes, melanin, the pigment responsible for skin color, cannot be produce. Normally, enzymes are made by cells using a gene or genes from the DNA. However, if a person has a mutation so that either they do not produce enough melanin or they cannot properly make melanin, or they cannot manufacture melanin period, or another such problem, the person will be an albino- they will lack pigmentation.

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Q: How are people albino due to a lack of enzymes?
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