There are a few companies that control the vast majority of tobacco distribution in North America, and they are collectively referred to as Big Tobacco.
Tobacco was THE big cash crop for Virginia.
North Carolina was a major producer of tobacco and pine.
North Carolina is a major producer of tobacco and pine tar.
Tobacco is a big crop in Zimbabwe.
Cotton and tobacco are the two big ones.
A big one
tobacco
a big black block
You need to be a bit more specific... This question doesn't make much sense. Are you looking for a specific case? I think we all know that tobacco contains nicotine, I haven't read any specific case where big tobacco lied about their products containing nicotine.
tobacco was a big material
It depends on how big their plantation was