Drugs with a low therapeutic index have a narrow margin of safety.
100
The therapeutic index of drugs is the ratio between the amount of drug needed to kill 50% of the cells of the experimental animals and the dose needed for 50% of the cells to respond. The larger the therapeutic index, the safer the drug.
It is for certain drugs such as Digoxin as they have such a narrow therapeutic index. For drugs with a wide range of therapeutic index, the best measure of safety is the maximum daily dose, its effect on the patient and what other drugs it interacts with. Ask your pharmacist for specific safety questions on your specific drugs.
How to calculate machine price index?
to calculate viscosity index
Bond's work index one of the most acceptable approach to calculate the grindability index.
I think the answer you're asking for is 2.5, but you should be including the n of the entire poopulation.
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Severity Index= no. of fatal accidents / total no. of injury accidents
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