Start by determining for sure where it's coming from. You may possibly need to replace a rear seal, and that's going to involve dropping the transaxle, removing the old seal, and driving the new one in. If you're scratching your head wondering how to go about doing this, you're probably in over your head, and would be better advised to leave this to a professional.
First you have to determime the source and cause of the leak. If it is the rear main oil seal in the engine, either the transmission or the engine has to come out to replace that seal.
The 2006 Ford Escape has an inline 4 engine.
That's a ( 3.0 liter V6 engine ) in a 2006 Ford Escape XLT with 4 speed automatic transmission
The 2006 Ford Escape has a 5-speed manual.
The 2006 Ford Escape has a 3.0L V6 engine which gives you between 18-23 miles per gallon. There is also 2006 Ford Escape XLS models that have a 2.3 4-cyl. engine. This model gives you 21-27 miles per gallon.
Mounted between the engine and the transmission.
The 2006 Ford Escape has a 2.3 L base engine size.
The 2006 Ford Escape's engine produces 153 hp @ 5800 rpm.
The 2006 Ford Escape's engine produces 152 ft-lbs. @ 4250 rpm.
That is a 2006 Ford Escape with the ( 3.0 liter V6 engine )
Mercron v auto transmission fluid
On the transmission bellhousing.
a illustation of odyssey 2006 engine