Scientists had already reached the milestone of fully sequencing their first genome that of the FX174 bacteriophage, whose 5,375 nucleotides had been determined in 1977 (Sanger et al., [ 1977b) but this endeavor proved much easier than sequencing the genomes of more complex life forms. Indeed, the prospect of sequencing the 1 million base pairs of the E. coli genome or the 3 billion nucleotides of the human genome seemed close to impossible. ..............
The genetic material of the phage can be passed on to future generations of cells.
becoz they can incorporate more than 10kb size of wanted segment into bacteriophage genome which is helpful for production of genome libraries or cDna libraries
Lysogenic cycle
phages can range from 50nm to 200nm.This dimension dont favorizied virused to enty intairlly into their host bacteria.Cell wall of bacteria it is composed of peptidoglycan a glicoprotein that it protect bacteria again enviromental stress and agents.For this reason phages have evolved to inject their genome to the host bacteria.
This action is called lysis of the host cell.
Lysogenic is when the virus enters and binds into the hosts DNA and one could replicate slowly or two when the virus sense the host cell is about to die, the virus will go into lyic cycle and replicate and kills the host cell.
The genetic material of the phage can be passed on to future generations of cells.
bacteriophage
Genetic material of a bacteriophage , joined into the genome of a bacterium and able to produce phages if activated
becoz they can incorporate more than 10kb size of wanted segment into bacteriophage genome which is helpful for production of genome libraries or cDna libraries
Lysogenic cycle
Lysogenic cycle
A bacteriophage ( virus that infect bacteria) can multiply in a cell by two ways:lytic and lysogenic cycle.In lytic cycle, the phage DNA enters the cell, replicate and assembled within the cell and released outside by rupturing the host. It continues to invade the other bacteria.In case of lysogenic cycle the phage DNA once it enter the host cell gets integrated into the host genome and multiply along with host DNA. It remains latent. Upon proper induction, it undergoes lytic cycle again.The viruses that multiply by integrating into the host genome are widely used in gene therapy.
phages can range from 50nm to 200nm.This dimension dont favorizied virused to enty intairlly into their host bacteria.Cell wall of bacteria it is composed of peptidoglycan a glicoprotein that it protect bacteria again enviromental stress and agents.For this reason phages have evolved to inject their genome to the host bacteria.
This action is called lysis of the host cell.
bacteriophage
Virus penetrates its genetic material into the host. The genome is then inserted randomly on a point of the host genome. Since it is an random event, it can block a pathway of that particular or cause any mutation due to the insertion of viral genome.