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A mutation in a gene can change the amino acid sequence of the protein the gene makes. These alterations in the proteins' primary structure may affect the secondary, tertiary, and quaternary structure, all which have to be exact for proper functioning.

The mutation in a gene can also put a STOP message in the sequence so the protein is terminated prematurely, leading to a truncated polypeptide. Some polypeptides simply won't work, and when critical proteins are not functioning, the cell can cease to run metabolic reactions or undergo mitosis. Other polypeptides will become deleterious and directly harm the cell.

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12y ago
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9y ago

Mutations in DNA affect the function of genes in various ways. The proteins which are found in the genes may be prevented from the normal functioning and this may also alter the type of proteins formed among others.

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11y ago

DNA codes for the sequence of amino acids in proteins. If there is a mutation in DNA, it can lead to a DNA sequence coding for the wrong amino acid. When the wrong amino acid goes into a protein, it changes the chain, causing it to function differently or to not function at all.

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14y ago

Cells make mistakes in copying their own DNA, inserting an incorrect base or even skipping a base as the new strand is put together.

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14y ago

It changes the rate of growth that cell typically undergo.

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14y ago

When the mutation grows inside of you so does the cell. It becomes bigger and bigger every time the mutation grows i think

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15y ago

that would depend on the nature of the mutation,

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Q: How can mutation in DNA disrupt proper functioning?
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Some general effects of a mutation are changes in DNA/RNA sequences and plausibly alteration of the product of a gene or the prevention of a gene from functioning properly.


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