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Steroid drugs do lower your immune response and can put you at risk to catch some viruses. Ask the health care professional who prescribed the steroid drug and knows why you are taking it what extra precautions you should take, or ask your pharmacist. The pharmacists at drugstores in the US are available for consultation like this. Ask in advance if you need an appointment (it would be a good idea since they can schedule you when the pharmacist who is most knowledgeable on the subject is on duty and at a time with the fewest anticipated interruptions.)

Having said that, you should always consider yourself susceptible to HIV and consider everyone with whom you have sexual relations capable of transmitting STDs like HIV. Take all precautions, especially using condoms, whether you are taking steroids or not.

The following is one explanation online of the effects of steroids on the immune system:

One of the actions of prednisone is to weaken the body's immune system. This effect is beneficial when treating Allergies or so-called "autoimmune" diseases like Arthritis, lupus, ulcerative colitis and Crohn's disease. However, whenever you weaken the immune system, you increase the body's susceptibility to infection.

Prednisone does not make an individual more likely to get a flu or catch a cold. But, it can increase susceptibility to chickenpox (varicella) and other herpes viruses. Individuals, who have recovered from tuberculosis, or TB, can experience reactivation of the disease when on prednisone. If you have not previously had chickenpox, tell your doctor. Do not take prednisone if you have tuberculosis (active or inactive), shingles or other herpes infection of eyes, lips, or genitals. You should not be vaccinated against any infectious disease while you are on prednisone especially live polio vaccine. Allergy skin tests and TB skin tests will usually be invalid while you are on prednisone. A small number of patients on prednisone develop yeast infections of the mouth (thrush) or vagina. Fortunately, effective medications are available to combat this problem should it occur.

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Q: How can taking steroids put someone at risk for HIV?
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