Its action can be prolonged by using crystalline zinc insulin complexes, Lente preparations or protamine zinc insulin complexes. All of these complexes are in suspended form for subcutaneous administration.
Extracted insulin is usually purified by recrystallisation from solutions in the presence of ZnCl2.
yes
The mechanism of action of insulin in diabetes is to inhibit its production.
bacteria itself is not the treatment. we use the bacteria to produce insulin, we do so by inserting the gene into their plasmids and trigger them to produce the insulin. the insulin is extracted and used.
The insulin gene will be extracted from cells from an animal such as a pig, and placed into the loop of DNA in a microorganism. When the microorganism reproduces, the DNA gene will reproduce with it, and this is repeated again and again and the micro-organsms will produce insulin. Whe a sufficient amount of microorganisms have been grown, the insulin will be extracted and used in medicine
all current insulins preparation contain zinc (Katzung & Trevors pharmacology, 7th editon page 347). the problem with insulin is that is has a half life of 3 minutes so duration of action is short, imagine for patient to inject them self so frequently than already 1-5 x/day Zinc and protamine added in the insulin preparation to prolonged their duration of action. The ratio of zinc to insulin influences the rate of release of active hormones. I hope this information is helpful fredy
The insulin gene will be extracted from cells from an animal such as a pig, and placed into the loop of DNA in a microorganism. When the microorganism reproduces, the DNA gene will reproduce with it, and this is repeated again and again and the micro-organsms will produce insulin. Whe a sufficient amount of microorganisms have been grown, the insulin will be extracted and used in medicine
Insulin can come from a number of sources. It is sometimes extracted from the pancreas of a pig, but it can also be made by genetically engineered bacteria. So for a particular batch of insulin, you would have to find out how it was made.
chromium
Chromium
When you do cardiovascular fitness, muscle glycogen gets used up. When your body works to restore the glycogen your insulin action is heightened. Any type of physical activity makes your insulin action work better.
early method of getting insulin was from the pancreas of slaughtered cattle[mostly pigs]... However now a days it is prepared by the use of biotechnology. insulin consists of two strands of peptide chains [A and B].. the DNA coding for peptide chain A and chain B were extracted and then were inserted in bacteria E.coli.... this bateria then replicates and forms multiple amount of chain A and B which are then extracted and joined by disulphide bonds.... this forms insulin.