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all current insulins preparation contain zinc (Katzung & Trevors pharmacology, 7th editon page 347).

the problem with insulin is that is has a half life of 3 minutes so duration of action is short, imagine for patient to inject them self so frequently than already 1-5 x/day

Zinc and protamine added in the insulin preparation to prolonged their duration of action. The ratio of zinc to insulin influences the rate of release of active hormones.

I hope this information is helpful

fredy

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16y ago

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