through a prescription only through your doctor and thru a pharmacy
Temozolomide is a drug used in the treatment of cancer in the brain.
Temozolomide is prescription drug. You must have to consult with doctor before using it. The more information about temozolomide and all anti cancer medication is available oddwayinternational.com .
Temozolomide is a kind of medication that is prescribed to patients suffering from brain tumors and skin cancer. Temozolomide works by interfering with the increase of cancer cells and in so doing, slows their growth and multiplication in the body. Constipation is one of the common side effects of this drug. If you get constipated while taking temozolomide(http://www.guidechem.com/cas-856/85622-93-1.html), you can do as the following: Make sure to eat enough fiber; drink enough water; add a magnesium supplement; add 30 minutes of exercise to your day; consult a doctor.
It says no but if you do drink very little and not every week. It supposedly can cause depression if you have to much on it.
Yes, There is a drug named Temozolomide(Temodar) and it has shown some activity against Lung Cancer too. Find more about it here: http://www.virtualtrials.com/temodar/temodar.cfm
Temozolomide is used to treat brain cancers such as anaplastic astrocytoma, glioblastoma multiforme (GBM), and gliomas. Temozolomide may also be used to treat other types of cancer. More than 10 in every 100 people have one or more of the side effects listed below. Nausea and vomiting: anti-sickness drugs can be given to reduce or prevent these symptoms. Please tell the doctor or nurse if the sickness is not controlled or persists. Hair loss: patients may lose some or all of his or her hair or it may become thinner. This is temporary and the hair will grow back once the treatment is finished. Increased risk of getting an infection from a drop in white blood cells: it is harder to fight infections and you can become very ill. You may have headaches, aching muscles, a cough, sore throat, pain passing urine or feel cold and shivery.
žNitrogen mustards: such as mechlorethamine (nitrogen mustard), chlorambucil, Cyclophosphamide (Cytoxan), ifosfamide, and melphalanžžNitrosoureas:streptozocin, carmustine (BCNU), and lomustinežAlkyl sulfonates: busulfanžžTriazines: dacarbazine (DTIC) and temozolomide (Temodar)žžEthylenimines: thiotepa and altretamine (hexamethylmelamine)žThe platinum drugs (cisplatin, carboplatin, and oxalaplatin) are sometimes grouped with alkylating agents because they kill cells in a similar way.
The J code for Temodar (temozolomide) is J9999. This code is used for billing purposes in Medicare and other insurance programs to indicate the administration of this chemotherapy medication. Temodar is typically provided in oral capsule form, so the J code may not always be directly applicable as it is often billed differently than injectable medications. Always check the latest coding guidelines for accurate billing.
Certain chemotherapy drugs can penetrate the blood-brain barrier, including temozolomide, a standard treatment for glioblastoma, and carmustine, which is often used for brain tumors. Other agents like methotrexate and cytarabine may also reach the central nervous system to some extent, especially when used in high doses or via intrathecal administration. Additionally, some newer targeted therapies and immunotherapies are being developed to improve drug delivery to the brain.
A glioblastoma (GBM) tumor itself can not cause constipation, unless the tumor location is affecting bowel movement or colon muscle coordination. Commonly, however, constipation in GBM patients is caused by chemotherapy drugs. It's important to stay on top of constipation issues for any cancer patient taking drugs, since a "small" issue like this can easily become a trip to the hospital emergency room for an enema. Even if patients have never suffered from constipation prior to cancer, they should consider taking prophylactic stool softeners while taking drugs which can cause constipation. Of course, many chemo drugs can also cause diarrhea. Some drugs, like the temozolomide (Temodar or Temodal) used in standard treatment of GBMs can cause constipation OR diarrhea; every patient reacts differently to drugs.
Brain tumors will kill ~13,000 people in the US this year, and they are the second leading cause of cancer deaths in children and young adults [1] Ruggiero A, Cefalo G, Garre ML, Massimino M, Colosimo C, Attina G, et al: Phase II trial of temozolomide in children with recurrent high-grade glioma. J Neurooncol 2005, 1-6.
DefinitionPrimary lymphoma of the brain is cancer of the lymph cells that starts in the brain.Alternative NamesBrain lymphoma; Cerebral lymphoma; Primary lymphoma of the central nervous system; Lymphoma - brainCauses, incidence, and risk factorsThe cause of primary brain lymphoma is unknown. It is more common in people ages 45 - 70.Patients who have a weakened immune system are at greater risk for primary lymphoma of the brain. Common causes of a weakened immune system include:HIVOrgan transplants (especially heart transplants)Primary lymphoma of the brain is also linked to Epstein-Barr Virus (EBV) infection, the virus that causes mononucleosis.The rate of primary brain lymphoma is rising, but it is still relatively rare.SymptomsChanges in speechChanges in visionConfusionFeverHallucinationsHeadachesNumbness to hot, cold, and painPersonality changesSeizuresWeakness in handsWeight lossSigns and testsThe following tests may be performed to help diagnose a primary lymphoma of the brain:Biopsy of the brainCSF cell countCSF total proteinHead CT scan or MRITreatmentThe condition is usually first treated with corticosteroids to control any local swelling and improve symptoms. However, chemotherapy may increase survival by 3 - 4 years, or longer. The chemotherapy is usually high doses of methotrexate given through a vein (intravenously) or a spinal tap(intrathecally).Treating patients with weakened immune systems is not as successful, but it is improving.Radiation therapy used to be the main treatment for primary lymphoma of the brain. Now it is usually reserved for treating patients who do not respond to chemotherapy.Treatment with multiple therapies (combination therapy) is common.Expectations (prognosis)The survival of untreated primary brain lymphoma is under 2 months. Treated with chemotherapy, patients often survive 3 - 4 years or more. About 40% of patients are alive at 5 years. In general, older patients have a worse outlook than younger patients.ComplicationsPossible complications include:Chemotherapy side effects, including low blood countsRadiation side effects, including confusion, headaches, nervous system (neurologic) problems, and tissue deathReturn (recurrence) of the lymphomaReferencesDeAngelis LM. Tumors of the central nervous system and intracranial hypertension and hypotension. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 199.National Cancer Institute. Primary CNS lymphoma treatment (PDQ). 2009. Accessed February 25, 2009.