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How can you tell if you are genetically a woman?

Updated: 9/27/2023
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Mjfan101

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10y ago

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By getting a genetic test. Karyotyping is one type of test. They can examine the external shape of the chromosomes. Or they could do more specific tests on a handful of genes.

Being chromosomally intersexed is possible, though this has nothing to do with gender identity. For instance, a mother of 3 was disqualified from the Olympics because karyotyping determined she was "male." She might have been born with a damaged sex chromosome which looked like a male chromosome.

There is also Complete Androgen Insensitivity Syndrome where in the 5th-12th week of gestation, the cascade needed to develop as a male does not occur. We all start out in the female direction until the genes on the Y chromosome start the differentiation cascade in males. So when they are born, they are assumed to be girls, and their gender identity is usually compatible with a female body. Often, parents may not be aware of this until puberty, when it does not occur on time. A gynecological exam may reveal that they have no uterus nor cervix, that their vagina is shallow, and that instead of ovaries, they have undescended testes. However, they do not become virile because their bodies do not respond to male hormones. They do make some estrogen since the body cannot use testosterone and it converts to estrogen via the aromatase enzyme. However, they may need supplemental hormones to develop female secondary features, and they might could use surgery to improve their ability to have sex.

An even rarer gender condition produces what seems to be spontaneous sex changes. What happens is that part of the gender differentiation cascade doesn't occur, and it is similar to CAIS as described above. However, when the person turns 12-14, male primary sexual development occurs. The irony to this is that it happens in locations where altering birth records is not allowed. So male development occurs, but is late.

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