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The settlement in the west affected the native Americans that lived there because once us Americans kept on pushing west after making Ohio a state we pushed into new areas .we settled in the territory of Indiana and other lands further west and the tide of settlement had a grave impact on native Americans like exposing them to disease's such as small pox,measles,and influenza killed thousands of them.and settlers took over a large part of there hunting grounds.took the forest for there farming. native Americans tradition,pover,home,life,and population declined.and that's how the settlement in the west affected the native Americans)

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