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. by changing the number of mRNA bases that make up the codons

2. by preventing the ribosome from binding to the mRNA

3. by changing the sequence in amino acids brought to the ribosome

4. by creating codons with no complimentary anti-codons

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Kasandra Hegmann

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2y ago
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9y ago

Mutations can change the folding pattern of a protein. They can also change a protein's quaternary and tertiary structures. There are different kinds of mutations, such as point mutations and frame shift mutations.

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Wiki User

14y ago

A mutation is a change in the way bases in DNA are arranged. Since DNA is responsible for controlling the production of proteins in cells, a mutation has the potential to alter either the amount, or type (or both) of proteins produced by the cell.

For example, if I alter (mutate) the instructions included with a LEGO building set, then the resulting building will be different to one produced using unaltered (non-mutated) instructions.

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13y ago
Primary structure, the amino acid sequence, affects the secondary structure, which affects the tertiary structure, which affects the quaternary structure (if any). In short, the amino acid sequence affects the shape of the protein, and the function of a protein depends on its shape.
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13y ago

Absolutely - that's why mutations cause problems. This change in the polypeptide's sequence can cause misfolding or premature termination. The protein can become non-functional or deleterious to the organism.

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Q: How do mutations affect proteins?
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Related questions

Do mutations in genes affect traits?

Genes produce proteins that cause traits.


Why do mutations in gene affect traits?

Genes produce proteins that cause traits.


How can DNA-level mutations affect the structure of proteins?

DNA is formed out of proteins, mutations can cause the bonds between the chains to loosen or not form at all. It may also cause additonal bonds forming and changet the order of amino acids involved in the chain.


What is the mutated gene of the Charcot-Marie-Tooth disease?

CMT is caused by mutations in genes that produce proteins involved in the structure and function of either the peripheral nerve axon or the myelin sheath. Although different proteins are abnormal in different forms of CMT disease, all of the mutations affect the normal function of the peripheral nerves. The gene mutations in CMT disease are usually inherited.


Why does Mutations lead to the production of aberrant proteins?

'cause.


How a mutation during replication can affect a protein that is synthesized?

A mutation during replication can affect a protein that is synthesized in a variety of ways. Mutations can mess up the protein sequences and cause different proteins to be synthesized.


How does a mutation in a sex cell differ from a mutation in a non-sex cell?

Mutations in sex cells can be passed on to children. Mutations in sex cells only affect offspring. Mutations in sex cells do not affect the organism.


Do neutral mutations affect biodiversity?

Type your answer here... no, neutral mutations do not affect biodiversity as they are a simple change which does not affect the organism in any way


How are point mutations different from flame shift mutations?

Point mutations are when a single nucleotide is replaced by a different one, but this doesn't affect the length of the DNA sequence, which usually will not affect the way the protein that is produced. A phase shift (what I think you meant) mutation is caused by an addition or deletion of a base that changes the length of the sequence. This causes problems because codons to make proteins are in sets of 3 and deleting a nucleotide makes the reading frame different and will add incorrect amino acids to the proteins from the mutation on, resulting in an ineffective protein.


How can mutations affect protein synthesis in cells What is the result?

Mutations can be a source of genetic


What is the significance of mutations to living things?

Many, if not most, mutations are neutral, meaning that they have little or no effect on the expression of genes or the function of the proteins for which they code.


True or false about gene mutations are Point mutations affect just one nucleotide?

yes