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How do the carnitine shuttles work?

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Kooikeria

Lvl 1
8y ago
Updated: 8/21/2019

The carnitine shuttles help transport fatty acyl coA from the cytosol of the cell into the mitochondrial matrix. The acyl group is first transfered to a carnitine and it is catalyzed into fatty acyl-carnitine by carnitine acyltransferease I at the outer mitochondrial membrane. The fatty acyl-carnitine then moves through the intermembrane space of the mitochondria through the transporter carnitine-acylcarnitine translocase. When the acyl group reaches the matrix, it is transferred to mitochondrial CoA, it is catalyzed by carnitine acyltransferase II to reform fatty acyl CoA. The carnitine is regenerated and it moves back to the intermembrane space with the aid of the same transporter.

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8y ago

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Related Questions

What is the physiological significance of carnitine shuttles?

Carnitine shuttles play a role in fatty-acid metabolism. They are needed to transport fatty acids from the cytosol to the mitochondrial matrix. This process is necessary as fatty acyl CoA can only be oxidized in the mitochondrial matrix to release energy.Without the carnitine shuttles, the fatty acyl CoA cannot cannot undergo oxidation. The body's production of acetyl CoA hence decreases as acetyl CoA is one of the products generated by the oxidation of acyl CoA. Glucose production is not stimulated and this leads to hypoglycemia, impairing brain functions and potentially leading to the loss of consciousness.


What are the different types of carnitine available in the market?

The different types of carnitine available in the market include L-carnitine, acetyl-L-carnitine, and propionyl-L-carnitine. These forms of carnitine are commonly used as dietary supplements to support energy production and metabolism in the body.


What is n-acetyl l-carnitine used for?

N-acetyl-L-carnitine is a dietary supplement which breaks down in the body to produce carnitine. L-carnitine (the active isomer of carnitine) is useful in metabolism of fatty acids. Check the animation in the related links below to understand that biochemistry of L-carnitine


What is the difference between L-carnitine and L-carnitine tartrate?

L-carnitine is a naturally occurring amino acid that helps the body produce energy. L-carnitine tartrate is a specific form of L-carnitine that is commonly used in supplements. The main difference between the two is that L-carnitine tartrate is a combination of L-carnitine and tartaric acid, which may affect its absorption and effectiveness in the body.


Does sweet potato have l carnitine?

They do not. Meats are high in carnitine, dairy is moderate in carnitine, and trace amount can be found in peanuts and avocados.


When is the best time to take L-Carnitine?

Early in the morning on an empty stomach and before work-out!


What are the different types of L-carnitine available in the market?

There are three main types of L-carnitine available in the market: L-carnitine tartrate, acetyl-L-carnitine, and propionyl-L-carnitine. Each type has slightly different properties and potential benefits for health and fitness.


What is the difference between acetyl l carnitine hydrochloride and acetyl l carnitine?

Acetyl L-carnitine and acetyl L-carnitine hydrochloride are two forms of the same compound. The only difference lies in the type of salt they are combined with. Acetyl L-carnitine hydrochloride is the hydrochloride salt form of acetyl L-carnitine.


What is the difference between acetyl L-carnitine and L-carnitine?

One has acetyl in front of it.


What are the differences between L-carnitine L-tartrate and L-carnitine, and how do they affect athletic performance and muscle recovery?

L-carnitine L-tartrate and L-carnitine are two forms of the same compound, but with different properties. L-carnitine L-tartrate is more stable and better absorbed by the body compared to L-carnitine. In terms of athletic performance and muscle recovery, L-carnitine L-tartrate has been shown to improve exercise performance, reduce muscle damage, and enhance recovery after intense workouts. On the other hand, L-carnitine may also have some benefits for athletes, but research on its effects is more limited. Overall, L-carnitine L-tartrate is considered more effective for enhancing athletic performance and muscle recovery compared to L-carnitine.


What are the differences between l-carnitine acetyl and l-carnitine tartrate, and how do they impact their effectiveness as supplements?

L-carnitine acetyl and L-carnitine tartrate are two forms of the same compound, but with different chemical structures. L-carnitine acetyl is more easily absorbed by the body, while L-carnitine tartrate is better for improving exercise performance. The effectiveness of each as a supplement depends on the specific health goals and needs of the individual.


Can you take L-carnitine before bed?

Yes, there is a lot of energy required for your body to work at night since you do not eat at all for hours. Taking L-Carnitine before going to bed makes your body take the energy from your fat.