I think it really depends on the situation. No matter WHAT job she does she will ALWAYS be "Mrs. *First Name* Johnson" OR "Mrs. Ben Johnson."
I think the real question here is determined by the nature of the contact. For example:
1) If you were sending them a personal/business letter, a Christmas, Birthday, or other type of holiday card, AND you were sending it to their personal residence &/or mailing address, then honor her in her most important position/s as a wife/mother by addressing her as "Mrs."
2) If, on the other hand, you are sending this communication to her JOB, then address her accordingly - i.e. "Dr. Johnson" OR "Dr. *First Name* Johnson".
Address on envelope to a doctor: Dr. John Doe is the general form.
Senior Doctor first if it is a medical reason or unmarried, Man first if it is a married couple.
Same as to anybody else. Put the name and address of the person clearly in the center of the envelope.
Senator John Doe, MD
Whichever is the highest qualification, which would be a doctor as a mayor is elected not qualified.
When address to a doctor it should appear as: Dr. John Doe or John Doe, MD.
When addressing an envelope to the wife of a doctor who is not a doctor herself then and he is Dr. John Doe, then address the envelope to her as Mrs. John Doe or Ms. (Mrs.) Jane Doe.
Dr.wife and Mr.husband yeh I'm 13 and I'm smarter than a {insert age here} year old i'd LOL if you were 10
The proper way to address an envelope to a doctor office is to first input the name of the clinic. On the second line you can insert in care of or C/O with the doctor's name. On the third and fourth line you can insert the address, city, and zip code. Include any suite or floor numbers of the doctor's office on the third line.
That would be: "Dr. John and Mrs. Jane Whomsoever".
The envelope should read: Mr. John Doe & Dr. Jane Doe. If you don't know her first name then put: Mr. & Dr. John Doe.
* Dr. & Mrs. John Doe