You don't mention what part of SC you're leaving from. If it's the eastern part, you can always take 95 down to Jacksonville and 10 across to Biloxi, although that adds about 150 miles to the trip. If you're centrally located, take 20 as if you're going to Atlanta, take 129 to Macon and 80 to Columbus. Head for Auburn and take I-85 the rest of the way. If you're leaving from western South Carolina, there's nothing that makes a lot of sense. Pick a time when traffic won't be heavy around Atlanta.
It is 388.90 miles according to MapQuest.
The distance between Atlanta GA and Biloxi MS is about 390 road miles.
The shortest driving distance is 388 miles.
Google Maps estimates the driving time as 6 hours and 12 minutes.
495 miles
Biloxi, MS is pretty close.
It is 602 miles according to Google Maps.
It is 365 miles according to Google Maps.
394 miles
Biloxi, MS is 164 miles southeast of Jackson, MS
The driving distance from Austin, TX to Biloxi, MS is approximately 520 miles. The actual mileage may vary depending on the specific route taken.
438 miles taking this route:Take I-59 SOUTH, from Trenton, to U.S. 49 to GULFPORT, via U.S. 98 EAST at EXIT 59 in HATTIESBURG, MISSISSIPPI. To bypass BIRMINGHAM, take I-459 SOUTH (EXIT 137 off I-59 in ALABAMA onto I-459 SOUTH to TUSCALOOSA).Take U.S. 49 SOUTH to MS-67 SOUTH to BILOXI.Take MS-67 SOUTH to Biloxi.