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And means multiplication. So,

5C1 x 10C2 x 4C1

= 5 x 10!/(8!2!) x 4

= 20 x (10 x 9 x 8!)/(8! x 2 x 1)

= 20 x 5 x 9

= 900

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Q: How do you calculate combination of choosing 1 of 5 main dishes 2 of 10 sides and 1 of 4 desserts?
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