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In theory, an element is made up of just one kind of atom and a compound is made up of two or more different elements that have formed a chemical bond. Empirically, there are lots of tests and measurements that you can make, as a chemist, to investigate the nature of any given substance. It's really too complex a subject to present fully in this answer.

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Q: How do you distinguish between an element and compound theoretically and empirically?
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