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Ive never had experience but just look for signs like if they're eyes are bloodshot or if they're pupils are different sizes from what they usually are. It could be different cases like some people gain weight and some lose or They sleep a lot and they don't feel like eating much. Or if round they're eyes it's black and they sort of sag And they smell a little different.
Answer
Be suspicious of any change of activity, just as you would if someone were sick. Low skin tone and color, dull eyes might be present. Eating, sleeping and physical activity are also good indicators.
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