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How do you think the acid fast nature of mycobacterium contributes to it virulence?
Wiki User
∙ 9y ago
Mycobacteria grow slowly, are protected from lysis once phagocytized, are capbable of intracellular growth, resistant to gram staining, many antimicrobial drugs, and from desiccation(drying out). mycobacteria are hard to treat and require a long treatment
Wiki User
∙ 15y ago
Wiki User
∙ 9y agoThe acid-fast nature of mycobacterium contributes to its virulence because its waxy cell wall makes it hard for other cells to phagocytize it. The mycobacterium is therefore likely to live, reproduce and cause disease.
Wiki User
∙ 9y agoCell wall lipids resist drying and stress which allows it to survive. Cells are not digested by phagocytes. Mycolic acid is a wax like lipid on cell walls of acid fast organisms. Makes cell wall impermeable to most stains.
Wiki User
∙ 14y agoIt provides a coating that prevents an immune response from mounting and rather than causing an acute disease state, immediately progresses to a chronic disease state.
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