Cisapride is a gastroprokinetic agent medication. It works by stimulating serotonin receptors to increases acetylcholine release. The medication has been withdrawn for use by humans in most countries but is available for use in animals.
Cisapride is available only with a physician's prescription. Cisapride is sold in tablet and liquid forms.
Anyone who has bleeding, blockage, or leakage in the stomach or intestines should not take cisapride. Cisapride should not be used by anyone who has had an unusual reaction to the drug in the past.
cisapride (Propulsid), is used to treat nighttime heartburn resulting from gastroesophageal reflux disease (GERD).
Propulsid
cisapride
Cisapride has caused dangerous irregular heart-beats in a few people who took it with other medicines.
This medicine is effective in treating only nighttime heartburn, not daytime heartburn.
Epilepsy or history of seizures Kidney disease Liver disease.
The drug passes into breast milk and may affect nursing babies. Women who are breastfeeding and need to take this medicine should check with their physicians.
abdominal pain, bloating, gas, diarrhea, constipation, nausea, upper respiratory infections, inflammation of the nasal passages and sinuses, headache, and viral infections.
Antifungal drugs such as ketoconazole (Nizoral), miconazole (Monistat), and fluconazole (Diflucan) Antibiotics such as clarithromycin (Biaxin) and erythromycin (E-Mycin, ERYC) Blood-thinners such as warfarin (Coumadin) H2-blockers such as cimetidine
adults and children age 12 and over is 5-20 mg taken two to four times a day. The medicine should be taken 15 minutes before meals and at bedtime. For children under 12, the dose is based on body weight and should be determined by the child's physician.