How does Clostridium Perfringens attack and spread?

Answer 1

The mechanism for clostridium botulinum is that it prevents vesicle fusion of the neurotransmitter acetylcholine at the neuromuscular junction, where neurons connect with muscle. Acetylcholine is the molecule responsible for telling your muscle to move and botulism prevents this chemical messenger from leaving the neuron and reaching the muscle. The end results is silence, or paralysis. The tetanus toxin works in a similar way, however it prevents inhibitory chemical messages (glycine and GABA) from reaching the muscle and the end results is hyperactivity, or tetanus. Both result in paralysis.

Answer 2

C perfringens produce several exotoxins, in which alpha toxin is the most important. It mediates destruction of host cell membranes; enterotoxin inserts and disrupts membranes of mucosal cells.

Answer 3

The bacteria produce Botulinum Toxin (BTX) by anaerobic respiration, so it commonly occurs in canned-food containers, where there is no oxygen and they were not killed when the food was processed. The bacteria can be killed and the toxin destroyed with high pressures or high temperatures (boiling for a few minutes), for example when cooking food.
Botulinum toxin is the most powerful neurotoxin known to date. Only one gram of botulinum toxin would be enough to kill 14,000 people (if ingested), 1.25 million people if inhaled, or a staggering 8.3 million people if injected.

Answer 4

binary fission