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Circulatory system is closed system exept at cappilory level. Here fluid leks out at proximal end of capillaries. It carries with it oxygen and digested food materials, disolved in plasma except plasma proteins. They are supplied to tissue cells and in return you get the carbon bi oxide and wasre products of metabolism. They reenters the circulation at distal end of capillary. At proximal end of cappilary, you have about 30 mm of Mercury blood pressure and at distal end it is about 20 mm of mercury. Fluid is pulled back due to oncotic pressure of plasma proteins.

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Q: How does diffusion functions in the exchange of substances between blood and tissues?
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