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Gabapentin is structurally related to the neurotransmitter GABA (gamma-aminobutyric acid) but it does not modify or directly act upon GABA(A) or GABA(B) receptors. As with most brain chemical altering drugs they don't completely understand how gabapentin works in the brain but it is theorized that it probably causes brain cells to make more GABA. For those with epilepsy this increase in GABA helps control seizures.

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Q: How does gabapentin effect your brain?
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Gabapentin does not reduce irritation or inflammation. It affects your brain.


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