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How does lugol's iodine work?

Updated: 9/20/2023
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11y ago

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Lugol's iodine is an organic iodide preparation that helps reduce the vascularity of the thyroid gland prior to definitive surgery for Grave's disease. This is brought about by induction of the Wollf Chaikoff effect caused by the the exogenous iodide which causes suppression of TSH mediated stimulation of the thyroid and helps in its atrophy. But before this can be attempted, the patient must be rendered euthyroid, since the initial effect of iodine could cause aggravation of thyrotoxicosis in an already uncontrolled Grave's disease.

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11y ago
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Q: How does lugol's iodine work?
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